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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
LSM6
All Species:
40.3
Human Site:
Y72
Identified Species:
63.33
UniProt:
P62312
Number Species:
14
Phosphosite Substitution
Charge Score:
0.07
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P62312
NP_009011.1
80
9128
Y72
I
R
G
N
N
V
L
Y
I
S
T
Q
K
R
R
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_855162
356
39457
Y348
I
R
G
N
N
V
L
Y
I
S
T
Q
K
R
R
Cat
Felis silvestris
Mouse
Mus musculus
XP_001480905
80
9135
Y72
I
R
G
N
N
V
L
Y
I
S
T
Q
K
R
W
Rat
Rattus norvegicus
XP_002728645
98
11021
E72
I
R
G
N
N
G
L
E
Y
T
P
D
Q
F
V
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Frog
Xenopus laevis
P62321
86
9707
Y71
I
R
C
N
N
V
L
Y
I
R
G
V
E
E
E
Zebra Danio
Brachydanio rerio
NP_001002077
80
9067
Y72
L
R
G
N
N
V
L
Y
I
S
T
Q
K
R
K
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q24297
88
9721
Y73
I
R
C
N
N
V
L
Y
I
K
G
M
E
D
D
Honey Bee
Apis mellifera
XP_001121733
79
8991
Y71
I
R
G
N
N
V
L
Y
I
S
T
Q
K
R
R
Nematode Worm
Caenorhab. elegans
P34659
85
9231
Y73
I
R
C
N
N
V
L
Y
V
G
G
V
D
G
E
Sea Urchin
Strong. purpuratus
XP_799246
83
9286
Y76
I
R
G
N
N
V
L
Y
I
S
T
Q
K
R
F
Poplar Tree
Populus trichocarpa
XP_002311269
91
9820
Y79
I
R
G
N
N
V
L
Y
I
S
T
S
K
R
T
Maize
Zea mays
NP_001131392
95
10058
Y83
I
R
G
N
N
V
L
Y
I
S
T
T
K
R
T
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9SUM2
88
9846
Y72
I
R
C
N
N
V
L
Y
V
R
G
V
P
E
D
Baker's Yeast
Sacchar. cerevisiae
P54999
86
9641
N77
E
I
F
I
R
C
N
N
V
L
Y
I
R
E
L
Red Bread Mold
Neurospora crassa
A7UXE4
82
8876
F70
R
R
S
Y
G
D
A
F
V
R
G
N
N
V
M
Conservation
Percent
Protein Identity:
100
N.A.
N.A.
22.4
N.A.
97.5
76.5
N.A.
N.A.
N.A.
44.1
96.2
N.A.
39.7
87.5
37.6
91.5
Protein Similarity:
100
N.A.
N.A.
22.4
N.A.
97.5
77.5
N.A.
N.A.
N.A.
58.1
100
N.A.
52.2
92.5
55.2
91.5
P-Site Identity:
100
N.A.
N.A.
100
N.A.
93.3
40
N.A.
N.A.
N.A.
53.3
86.6
N.A.
53.3
100
46.6
93.3
P-Site Similarity:
100
N.A.
N.A.
100
N.A.
93.3
53.3
N.A.
N.A.
N.A.
60
100
N.A.
60
100
53.3
93.3
Percent
Protein Identity:
75.8
73.6
N.A.
38.6
38.3
58.5
Protein Similarity:
81.3
77.8
N.A.
55.6
50
70.7
P-Site Identity:
86.6
86.6
N.A.
46.6
0
6.6
P-Site Similarity:
86.6
86.6
N.A.
53.3
13.3
20
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
7
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
27
0
0
7
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
7
0
0
0
0
0
7
7
7
14
% D
% Glu:
7
0
0
0
0
0
0
7
0
0
0
0
14
20
14
% E
% Phe:
0
0
7
0
0
0
0
7
0
0
0
0
0
7
7
% F
% Gly:
0
0
60
0
7
7
0
0
0
7
34
0
0
7
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
80
7
0
7
0
0
0
0
67
0
0
7
0
0
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
7
0
0
54
0
7
% K
% Leu:
7
0
0
0
0
0
87
0
0
7
0
0
0
0
7
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
7
0
0
7
% M
% Asn:
0
0
0
87
87
0
7
7
0
0
0
7
7
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
7
0
7
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
40
7
0
0
% Q
% Arg:
7
94
0
0
7
0
0
0
0
20
0
0
7
54
20
% R
% Ser:
0
0
7
0
0
0
0
0
0
54
0
7
0
0
0
% S
% Thr:
0
0
0
0
0
0
0
0
0
7
54
7
0
0
14
% T
% Val:
0
0
0
0
0
80
0
0
27
0
0
20
0
7
7
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
7
% W
% Tyr:
0
0
0
7
0
0
0
80
7
0
7
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _