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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ARF6
All Species:
51.52
Human Site:
S158
Identified Species:
87.18
UniProt:
P62330
Number Species:
13
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P62330
NP_001654.1
175
20082
S158
V
Q
P
S
C
A
T
S
G
D
G
L
Y
E
G
Chimpanzee
Pan troglodytes
XP_001153159
148
17054
A115
N
D
R
E
M
R
D
A
I
I
L
I
F
A
N
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
Cat
Felis silvestris
Mouse
Mus musculus
Rat
Rattus norvegicus
P84082
181
20727
S162
I
Q
A
T
C
A
T
S
G
D
G
L
Y
E
G
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001512800
175
20010
T158
V
Q
P
S
C
A
T
T
G
E
G
L
C
E
G
Chicken
Gallus gallus
P26990
175
20078
T158
V
Q
P
S
C
A
T
T
G
D
G
L
Y
E
G
Frog
Xenopus laevis
P51645
175
20169
S158
V
Q
P
S
C
A
A
S
G
D
G
L
Y
E
G
Zebra Danio
Brachydanio rerio
NP_956287
175
20110
T158
V
Q
P
S
C
A
T
T
G
D
G
L
Y
E
G
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P40946
175
19987
S158
V
Q
P
S
C
A
T
S
G
D
G
L
S
E
G
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q10943
181
20503
S162
I
Q
A
T
C
A
T
S
G
D
G
L
Y
E
G
Sea Urchin
Strong. purpuratus
XP_001191776
205
23738
S188
V
Q
P
A
C
A
T
S
G
E
G
L
L
E
G
Poplar Tree
Populus trichocarpa
Maize
Zea mays
P49076
181
20642
T162
I
Q
S
T
C
A
T
T
G
E
G
L
Y
E
G
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
P36397
181
20590
S162
I
Q
S
T
C
A
T
S
G
E
G
L
Y
E
G
Baker's Yeast
Sacchar. cerevisiae
P19146
181
20639
S162
I
Q
S
T
C
A
T
S
G
E
G
L
Y
E
G
Red Bread Mold
Neurospora crassa
Q7RVM2
185
20961
T165
I
Q
A
T
C
A
T
T
G
D
G
L
F
E
G
Conservation
Percent
Protein Identity:
100
84.5
N.A.
N.A.
N.A.
N.A.
68.5
N.A.
93.7
99.4
97.1
98.8
N.A.
96.5
N.A.
67.9
70.2
Protein Similarity:
100
84.5
N.A.
N.A.
N.A.
N.A.
82.3
N.A.
98.8
100
97.7
100
N.A.
97.7
N.A.
82.3
77
P-Site Identity:
100
0
N.A.
N.A.
N.A.
N.A.
80
N.A.
80
93.3
93.3
93.3
N.A.
93.3
N.A.
80
80
P-Site Similarity:
100
20
N.A.
N.A.
N.A.
N.A.
93.3
N.A.
93.3
100
93.3
100
N.A.
93.3
N.A.
93.3
93.3
Percent
Protein Identity:
N.A.
69.6
N.A.
69
65.1
67
Protein Similarity:
N.A.
83.4
N.A.
83.4
81.2
82.1
P-Site Identity:
N.A.
66.6
N.A.
73.3
73.3
66.6
P-Site Similarity:
N.A.
93.3
N.A.
93.3
93.3
93.3
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
22
8
0
93
8
8
0
0
0
0
0
8
0
% A
% Cys:
0
0
0
0
93
0
0
0
0
0
0
0
8
0
0
% C
% Asp:
0
8
0
0
0
0
8
0
0
58
0
0
0
0
0
% D
% Glu:
0
0
0
8
0
0
0
0
0
36
0
0
0
93
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
15
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
93
0
93
0
0
0
93
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
43
0
0
0
0
0
0
0
8
8
0
8
0
0
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
0
0
0
0
0
0
0
0
0
0
8
93
8
0
0
% L
% Met:
0
0
0
0
8
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
8
0
0
0
0
0
0
0
0
0
0
0
0
0
8
% N
% Pro:
0
0
50
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
93
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
8
0
0
8
0
0
0
0
0
0
0
0
0
% R
% Ser:
0
0
22
43
0
0
0
58
0
0
0
0
8
0
0
% S
% Thr:
0
0
0
43
0
0
86
36
0
0
0
0
0
0
0
% T
% Val:
50
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
65
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _