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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: ARF6 All Species: 40.91
Human Site: Y150 Identified Species: 69.23
UniProt: P62330 Number Species: 13
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P62330 NP_001654.1 175 20082 Y150 R I R D R N W Y V Q P S C A T
Chimpanzee Pan troglodytes XP_001153159 148 17054 I107 R Q E L H R I I N D R E M R D
Rhesus Macaque Macaca mulatta
Dog Lupus familis
Cat Felis silvestris
Mouse Mus musculus
Rat Rattus norvegicus P84082 181 20727 Y154 S L R Q R N W Y I Q A T C A T
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001512800 175 20010 Y150 R V R D R N W Y V Q P S C A T
Chicken Gallus gallus P26990 175 20078 Y150 R I R D R N W Y V Q P S C A T
Frog Xenopus laevis P51645 175 20169 Y150 R I R D R N W Y V Q P S C A A
Zebra Danio Brachydanio rerio NP_956287 175 20110 Y150 R I R D R N W Y V Q P S C A T
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P40946 175 19987 Y150 R I R D R N W Y V Q P S C A T
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans Q10943 181 20503 Y154 S L R N R S W Y I Q A T C A T
Sea Urchin Strong. purpuratus XP_001191776 205 23738 F180 K I R D R N W F V Q P A C A T
Poplar Tree Populus trichocarpa
Maize Zea mays P49076 181 20642 Y154 S L R Q R H W Y I Q S T C A T
Rice Oryza sativa
Thale Cress Arabidopsis thaliana P36397 181 20590 Y154 S L R Q R H W Y I Q S T C A T
Baker's Yeast Sacchar. cerevisiae P19146 181 20639 F154 S I R N R P W F I Q S T C A T
Red Bread Mold Neurospora crassa Q7RVM2 185 20961 Y157 S L R Q R S W Y I Q A T C A T
Conservation
Percent
Protein Identity: 100 84.5 N.A. N.A. N.A. N.A. 68.5 N.A. 93.7 99.4 97.1 98.8 N.A. 96.5 N.A. 67.9 70.2
Protein Similarity: 100 84.5 N.A. N.A. N.A. N.A. 82.3 N.A. 98.8 100 97.7 100 N.A. 97.7 N.A. 82.3 77
P-Site Identity: 100 6.6 N.A. N.A. N.A. N.A. 60 N.A. 93.3 100 93.3 100 N.A. 100 N.A. 53.3 80
P-Site Similarity: 100 6.6 N.A. N.A. N.A. N.A. 80 N.A. 100 100 93.3 100 N.A. 100 N.A. 86.6 100
Percent
Protein Identity: N.A. 69.6 N.A. 69 65.1 67
Protein Similarity: N.A. 83.4 N.A. 83.4 81.2 82.1
P-Site Identity: N.A. 53.3 N.A. 53.3 53.3 53.3
P-Site Similarity: N.A. 80 N.A. 80 80 80
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 0 0 0 0 22 8 0 93 8 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 93 0 0 % C
% Asp: 0 0 0 50 0 0 0 0 0 8 0 0 0 0 8 % D
% Glu: 0 0 8 0 0 0 0 0 0 0 0 8 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 15 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % G
% His: 0 0 0 0 8 15 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 50 0 0 0 0 8 8 43 0 0 0 0 0 0 % I
% Lys: 8 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % K
% Leu: 0 36 0 8 0 0 0 0 0 0 0 0 0 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 8 0 0 % M
% Asn: 0 0 0 15 0 58 0 0 8 0 0 0 0 0 0 % N
% Pro: 0 0 0 0 0 8 0 0 0 0 50 0 0 0 0 % P
% Gln: 0 8 0 29 0 0 0 0 0 93 0 0 0 0 0 % Q
% Arg: 50 0 93 0 93 8 0 0 0 0 8 0 0 8 0 % R
% Ser: 43 0 0 0 0 15 0 0 0 0 22 43 0 0 0 % S
% Thr: 0 0 0 0 0 0 0 0 0 0 0 43 0 0 86 % T
% Val: 0 8 0 0 0 0 0 0 50 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 93 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 79 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _