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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PSMC6
All Species:
22.73
Human Site:
S377
Identified Species:
38.46
UniProt:
P62333
Number Species:
13
Phosphosite Substitution
Charge Score:
0.15
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P62333
NP_002797.3
389
44173
S377
A
V
R
K
V
A
D
S
K
K
L
E
S
K
L
Chimpanzee
Pan troglodytes
XP_519765
389
44101
S377
A
V
R
K
V
A
D
S
K
K
L
E
S
K
L
Rhesus Macaque
Macaca mulatta
XP_001082028
389
44038
S377
A
V
R
K
V
A
D
S
K
K
L
E
S
K
L
Dog
Lupus familis
Cat
Felis silvestris
Mouse
Mus musculus
P46471
433
48629
E406
A
R
R
K
I
A
T
E
K
D
F
L
E
A
V
Rat
Rattus norvegicus
Q63347
433
48556
E406
A
R
R
K
I
A
T
E
K
D
F
L
E
A
V
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001521658
400
45289
S388
A
V
R
K
V
A
D
S
K
K
L
E
S
K
L
Chicken
Gallus gallus
NP_001006494
389
44155
S377
A
V
R
K
V
A
D
S
K
K
L
E
S
K
L
Frog
Xenopus laevis
P46470
461
52229
N435
L
I
K
P
T
R
F
N
R
R
I
I
T
N
S
Zebra Danio
Brachydanio rerio
NP_001003832
389
44206
S377
A
V
R
K
V
A
D
S
K
K
L
E
S
K
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
O18413
405
45839
A387
E
D
F
E
M
A
V
A
K
V
M
Q
K
D
S
Honey Bee
Apis mellifera
XP_623784
393
44469
N381
A
V
R
K
V
S
D
N
K
K
L
E
S
K
L
Nematode Worm
Caenorhab. elegans
O17071
406
45840
A394
A
V
R
K
V
G
D
A
K
R
L
E
T
K
L
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9SEI3
399
44798
A383
A
V
R
K
L
S
E
A
K
K
L
E
S
S
S
Baker's Yeast
Sacchar. cerevisiae
P53549
437
49390
V425
A
V
R
K
V
A
E
V
K
K
L
E
G
T
I
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
96.6
98.1
N.A.
N.A.
42.2
42.4
N.A.
92.2
99.7
41.2
97.1
N.A.
45.9
89.5
78.5
N.A.
Protein Similarity:
100
97.9
98.7
N.A.
N.A.
60
59.8
N.A.
93.5
100
56.1
99.2
N.A.
62.4
95.6
89.9
N.A.
P-Site Identity:
100
100
100
N.A.
N.A.
33.3
33.3
N.A.
100
100
0
100
N.A.
13.3
86.6
73.3
N.A.
P-Site Similarity:
100
100
100
N.A.
N.A.
46.6
46.6
N.A.
100
100
46.6
100
N.A.
46.6
100
93.3
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
74.4
61.3
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
85.4
74.6
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
60
66.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
86.6
80
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
86
0
0
0
0
72
0
22
0
0
0
0
0
15
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
8
0
0
0
0
58
0
0
15
0
0
0
8
0
% D
% Glu:
8
0
0
8
0
0
15
15
0
0
0
72
15
0
0
% E
% Phe:
0
0
8
0
0
0
8
0
0
0
15
0
0
0
0
% F
% Gly:
0
0
0
0
0
8
0
0
0
0
0
0
8
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
8
0
0
15
0
0
0
0
0
8
8
0
0
8
% I
% Lys:
0
0
8
86
0
0
0
0
93
65
0
0
8
58
0
% K
% Leu:
8
0
0
0
8
0
0
0
0
0
72
15
0
0
58
% L
% Met:
0
0
0
0
8
0
0
0
0
0
8
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
15
0
0
0
0
0
8
0
% N
% Pro:
0
0
0
8
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
8
0
0
0
% Q
% Arg:
0
15
86
0
0
8
0
0
8
15
0
0
0
0
0
% R
% Ser:
0
0
0
0
0
15
0
43
0
0
0
0
58
8
22
% S
% Thr:
0
0
0
0
8
0
15
0
0
0
0
0
15
8
0
% T
% Val:
0
72
0
0
65
0
8
8
0
8
0
0
0
0
15
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _