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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: PSMC6 All Species: 22.73
Human Site: S377 Identified Species: 38.46
UniProt: P62333 Number Species: 13
    Phosphosite Substitution
    Charge Score: 0.15
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P62333 NP_002797.3 389 44173 S377 A V R K V A D S K K L E S K L
Chimpanzee Pan troglodytes XP_519765 389 44101 S377 A V R K V A D S K K L E S K L
Rhesus Macaque Macaca mulatta XP_001082028 389 44038 S377 A V R K V A D S K K L E S K L
Dog Lupus familis
Cat Felis silvestris
Mouse Mus musculus P46471 433 48629 E406 A R R K I A T E K D F L E A V
Rat Rattus norvegicus Q63347 433 48556 E406 A R R K I A T E K D F L E A V
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001521658 400 45289 S388 A V R K V A D S K K L E S K L
Chicken Gallus gallus NP_001006494 389 44155 S377 A V R K V A D S K K L E S K L
Frog Xenopus laevis P46470 461 52229 N435 L I K P T R F N R R I I T N S
Zebra Danio Brachydanio rerio NP_001003832 389 44206 S377 A V R K V A D S K K L E S K L
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster O18413 405 45839 A387 E D F E M A V A K V M Q K D S
Honey Bee Apis mellifera XP_623784 393 44469 N381 A V R K V S D N K K L E S K L
Nematode Worm Caenorhab. elegans O17071 406 45840 A394 A V R K V G D A K R L E T K L
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9SEI3 399 44798 A383 A V R K L S E A K K L E S S S
Baker's Yeast Sacchar. cerevisiae P53549 437 49390 V425 A V R K V A E V K K L E G T I
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 96.6 98.1 N.A. N.A. 42.2 42.4 N.A. 92.2 99.7 41.2 97.1 N.A. 45.9 89.5 78.5 N.A.
Protein Similarity: 100 97.9 98.7 N.A. N.A. 60 59.8 N.A. 93.5 100 56.1 99.2 N.A. 62.4 95.6 89.9 N.A.
P-Site Identity: 100 100 100 N.A. N.A. 33.3 33.3 N.A. 100 100 0 100 N.A. 13.3 86.6 73.3 N.A.
P-Site Similarity: 100 100 100 N.A. N.A. 46.6 46.6 N.A. 100 100 46.6 100 N.A. 46.6 100 93.3 N.A.
Percent
Protein Identity: N.A. N.A. N.A. 74.4 61.3 N.A.
Protein Similarity: N.A. N.A. N.A. 85.4 74.6 N.A.
P-Site Identity: N.A. N.A. N.A. 60 66.6 N.A.
P-Site Similarity: N.A. N.A. N.A. 86.6 80 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 86 0 0 0 0 72 0 22 0 0 0 0 0 15 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 8 0 0 0 0 58 0 0 15 0 0 0 8 0 % D
% Glu: 8 0 0 8 0 0 15 15 0 0 0 72 15 0 0 % E
% Phe: 0 0 8 0 0 0 8 0 0 0 15 0 0 0 0 % F
% Gly: 0 0 0 0 0 8 0 0 0 0 0 0 8 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 8 0 0 15 0 0 0 0 0 8 8 0 0 8 % I
% Lys: 0 0 8 86 0 0 0 0 93 65 0 0 8 58 0 % K
% Leu: 8 0 0 0 8 0 0 0 0 0 72 15 0 0 58 % L
% Met: 0 0 0 0 8 0 0 0 0 0 8 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 15 0 0 0 0 0 8 0 % N
% Pro: 0 0 0 8 0 0 0 0 0 0 0 0 0 0 0 % P
% Gln: 0 0 0 0 0 0 0 0 0 0 0 8 0 0 0 % Q
% Arg: 0 15 86 0 0 8 0 0 8 15 0 0 0 0 0 % R
% Ser: 0 0 0 0 0 15 0 43 0 0 0 0 58 8 22 % S
% Thr: 0 0 0 0 8 0 15 0 0 0 0 0 15 8 0 % T
% Val: 0 72 0 0 65 0 8 8 0 8 0 0 0 0 15 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _