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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: TBPL1 All Species: 17.58
Human Site: S87 Identified Species: 22.75
UniProt: P62380 Number Species: 17
    Phosphosite Substitution
    Charge Score: 0.06
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P62380 NP_004856.1 186 20887 S87 G A R R L A R S L Q K L G F Q
Chimpanzee Pan troglodytes A6H907 376 41488 V277 A A R K Y A R V V Q K L G F P
Rhesus Macaque Macaca mulatta
Dog Lupus familis XP_859674 165 18612 E75 C T G A T S E E E A K F G A R
Cat Felis silvestris
Mouse Mus musculus P62340 186 20868 S87 G A R R L A R S L Q K L G F Q
Rat Rattus norvegicus A6H909 344 38336 V246 A A R K Y A R V V Q K L G F P
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001506923 368 39922 S272 G A R R L A R S L Q K L G F Q
Chicken Gallus gallus Q9YGV8 183 20515 C87 G A R R L A R C L Q K L G F Q
Frog Xenopus laevis Q9W6Z2 186 20942 S87 G A R R L A R S L Q K L G F Q
Zebra Danio Brachydanio rerio Q5U385 186 20743 C87 G A R R L A R C L Q K M G F K
Tiger Blowfish Takifugu rubipres Q6SJ94 322 35702 V224 A A R K Y A R V V Q K L G F P
Fruit Fly Dros. melanogaster P20227 353 38433 I254 A A R K Y A R I I Q K L G F P
Honey Bee Apis mellifera XP_396371 284 32113 S138 A A R R F A R S L Q K L G F K
Nematode Worm Caenorhab. elegans P32085 340 36629 I243 A A R K Y A R I V Q K L G F Q
Sea Urchin Strong. purpuratus P91809 265 29089 V166 A A R K Y A R V V Q K L G F A
Poplar Tree Populus trichocarpa XP_002325828 201 22422 I101 A A R K Y A R I I Q K L G F A
Maize Zea mays P50159 200 22277 I100 A A R K Y A R I I Q K L G F P
Rice Oryza sativa
Thale Cress Arabidopsis thaliana P28148 200 22378 I100 A A R K Y A R I V Q K L G F P
Baker's Yeast Sacchar. cerevisiae P13393 240 26985 I142 A S R K Y A R I I Q K I G F A
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 22.6 N.A. 86.5 N.A. 100 25.5 N.A. 48.6 96.2 92.4 78.4 26.4 21.2 41.2 25.2 30.1
Protein Similarity: 100 32.9 N.A. 88.7 N.A. 100 38.3 N.A. 49.4 97.8 95.6 90.3 40.3 35.4 51.4 35.5 44.9
P-Site Identity: 100 60 N.A. 13.3 N.A. 100 60 N.A. 100 93.3 100 80 60 60 80 66.6 60
P-Site Similarity: 100 73.3 N.A. 26.6 N.A. 100 73.3 N.A. 100 93.3 100 93.3 73.3 73.3 86.6 80 73.3
Percent
Protein Identity: 38.8 39 N.A. 39 30 N.A.
Protein Similarity: 58.2 58 N.A. 57 48.7 N.A.
P-Site Identity: 60 60 N.A. 60 46.6 N.A.
P-Site Similarity: 73.3 73.3 N.A. 73.3 73.3 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 62 89 0 6 0 95 0 0 0 6 0 0 0 6 17 % A
% Cys: 6 0 0 0 0 0 0 12 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % D
% Glu: 0 0 0 0 0 0 6 6 6 0 0 0 0 0 0 % E
% Phe: 0 0 0 0 6 0 0 0 0 0 0 6 0 95 0 % F
% Gly: 34 0 6 0 0 0 0 0 0 0 0 0 100 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 34 23 0 0 6 0 0 0 % I
% Lys: 0 0 0 56 0 0 0 0 0 0 100 0 0 0 12 % K
% Leu: 0 0 0 0 34 0 0 0 39 0 0 84 0 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 6 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 34 % P
% Gln: 0 0 0 0 0 0 0 0 0 95 0 0 0 0 34 % Q
% Arg: 0 0 95 39 0 0 95 0 0 0 0 0 0 0 6 % R
% Ser: 0 6 0 0 0 6 0 28 0 0 0 0 0 0 0 % S
% Thr: 0 6 0 0 6 0 0 0 0 0 0 0 0 0 0 % T
% Val: 0 0 0 0 0 0 0 23 34 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 56 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _