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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TBPL1
All Species:
15.15
Human Site:
T121
Identified Species:
19.61
UniProt:
P62380
Number Species:
17
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P62380
NP_004856.1
186
20887
T121
E
I
R
L
P
E
F
T
K
N
N
R
P
H
A
Chimpanzee
Pan troglodytes
A6H907
376
41488
V311
P
I
R
L
E
G
L
V
L
T
H
Q
Q
F
S
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_859674
165
18612
K101
Q
V
I
F
T
D
F
K
V
V
N
V
L
A
V
Cat
Felis silvestris
Mouse
Mus musculus
P62340
186
20868
T121
E
I
R
L
P
E
F
T
K
N
N
R
P
H
A
Rat
Rattus norvegicus
A6H909
344
38336
A280
P
I
R
L
E
I
L
A
L
T
H
R
Q
F
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506923
368
39922
E299
A
V
C
N
M
P
F
E
I
R
L
P
E
F
T
Chicken
Gallus gallus
Q9YGV8
183
20515
L117
N
M
P
F
E
I
R
L
P
E
F
T
K
N
N
Frog
Xenopus laevis
Q9W6Z2
186
20942
T121
E
I
R
L
N
E
F
T
K
Q
N
R
P
H
A
Zebra Danio
Brachydanio rerio
Q5U385
186
20743
T121
Q
I
R
L
I
E
F
T
K
N
N
R
P
I
A
Tiger Blowfish
Takifugu rubipres
Q6SJ94
322
35702
V258
P
I
R
L
E
G
L
V
L
T
H
Q
Q
F
S
Fruit Fly
Dros. melanogaster
P20227
353
38433
V288
P
I
R
L
E
G
L
V
L
T
H
C
N
F
S
Honey Bee
Apis mellifera
XP_396371
284
32113
S172
A
I
K
I
T
S
F
S
S
C
H
K
E
N
A
Nematode Worm
Caenorhab. elegans
P32085
340
36629
I271
S
C
D
V
R
F
P
I
Q
L
E
G
L
C
I
Sea Urchin
Strong. purpuratus
P91809
265
29089
V200
P
I
R
L
E
G
L
V
L
T
H
G
Q
F
S
Poplar Tree
Populus trichocarpa
XP_002325828
201
22422
A135
P
I
R
L
E
G
L
A
Y
S
H
G
A
F
S
Maize
Zea mays
P50159
200
22277
A134
P
I
R
L
E
G
L
A
Y
S
H
G
A
F
S
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
P28148
200
22378
A134
P
I
R
L
E
G
L
A
Y
S
H
S
A
F
S
Baker's Yeast
Sacchar. cerevisiae
P13393
240
26985
A176
P
I
R
L
E
G
L
A
F
S
H
G
T
F
S
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
22.6
N.A.
86.5
N.A.
100
25.5
N.A.
48.6
96.2
92.4
78.4
26.4
21.2
41.2
25.2
30.1
Protein Similarity:
100
32.9
N.A.
88.7
N.A.
100
38.3
N.A.
49.4
97.8
95.6
90.3
40.3
35.4
51.4
35.5
44.9
P-Site Identity:
100
20
N.A.
13.3
N.A.
100
26.6
N.A.
6.6
0
86.6
80
20
20
20
0
20
P-Site Similarity:
100
40
N.A.
33.3
N.A.
100
40
N.A.
13.3
13.3
86.6
86.6
40
33.3
60
13.3
33.3
Percent
Protein Identity:
38.8
39
N.A.
39
30
N.A.
Protein Similarity:
58.2
58
N.A.
57
48.7
N.A.
P-Site Identity:
20
20
N.A.
20
20
N.A.
P-Site Similarity:
40
40
N.A.
40
40
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
12
0
0
0
0
0
0
28
0
0
0
0
17
6
28
% A
% Cys:
0
6
6
0
0
0
0
0
0
6
0
6
0
6
0
% C
% Asp:
0
0
6
0
0
6
0
0
0
0
0
0
0
0
0
% D
% Glu:
17
0
0
0
56
23
0
6
0
6
6
0
12
0
0
% E
% Phe:
0
0
0
12
0
6
39
0
6
0
6
0
0
56
0
% F
% Gly:
0
0
0
0
0
45
0
0
0
0
0
28
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
56
0
0
17
0
% H
% Ile:
0
78
6
6
6
12
0
6
6
0
0
0
0
6
6
% I
% Lys:
0
0
6
0
0
0
0
6
23
0
0
6
6
0
0
% K
% Leu:
0
0
0
73
0
0
50
6
28
6
6
0
12
0
0
% L
% Met:
0
6
0
0
6
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
6
0
0
6
6
0
0
0
0
17
28
0
6
12
6
% N
% Pro:
50
0
6
0
12
6
6
0
6
0
0
6
23
0
0
% P
% Gln:
12
0
0
0
0
0
0
0
6
6
0
12
23
0
0
% Q
% Arg:
0
0
73
0
6
0
6
0
0
6
0
28
0
0
0
% R
% Ser:
6
0
0
0
0
6
0
6
6
23
0
6
0
0
50
% S
% Thr:
0
0
0
0
12
0
0
23
0
28
0
6
6
0
6
% T
% Val:
0
12
0
6
0
0
0
23
6
6
0
6
0
0
6
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
17
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _