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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TBPL1
All Species:
18.79
Human Site:
T148
Identified Species:
24.31
UniProt:
P62380
Number Species:
17
Phosphosite Substitution
Charge Score:
-0.06
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P62380
NP_004856.1
186
20887
T148
R
I
K
S
L
R
A
T
L
Q
I
F
S
T
G
Chimpanzee
Pan troglodytes
A6H907
376
41488
V338
R
M
I
K
P
R
I
V
L
L
I
F
V
S
G
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_859674
165
18612
A128
T
K
N
N
R
P
H
A
S
Y
E
P
E
L
H
Cat
Felis silvestris
Mouse
Mus musculus
P62340
186
20868
T148
R
I
K
S
L
R
A
T
L
Q
I
F
S
T
G
Rat
Rattus norvegicus
A6H909
344
38336
V307
K
M
V
K
P
Q
V
V
L
L
I
F
A
S
G
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506923
368
39922
R326
L
H
P
A
V
C
Y
R
I
K
T
L
R
A
T
Chicken
Gallus gallus
Q9YGV8
183
20515
T144
A
V
C
Y
R
I
K
T
L
R
A
T
L
Q
I
Frog
Xenopus laevis
Q9W6Z2
186
20942
T148
R
I
K
S
L
R
A
T
L
Q
I
F
S
T
G
Zebra Danio
Brachydanio rerio
Q5U385
186
20743
T148
R
I
K
N
L
R
S
T
V
Q
V
F
S
T
G
Tiger Blowfish
Takifugu rubipres
Q6SJ94
322
35702
V285
R
M
V
K
P
R
I
V
L
L
I
F
V
S
G
Fruit Fly
Dros. melanogaster
P20227
353
38433
V315
R
M
V
R
P
R
I
V
L
L
I
F
V
S
G
Honey Bee
Apis mellifera
XP_396371
284
32113
T199
K
L
K
E
P
K
A
T
L
K
I
F
S
T
G
Nematode Worm
Caenorhab. elegans
P32085
340
36629
M298
F
P
G
L
I
Y
R
M
V
K
P
R
V
V
L
Sea Urchin
Strong. purpuratus
P91809
265
29089
V227
R
M
V
K
P
R
I
V
L
L
I
F
V
S
G
Poplar Tree
Populus trichocarpa
XP_002325828
201
22422
V162
R
M
K
Q
P
K
I
V
L
L
I
F
V
S
G
Maize
Zea mays
P50159
200
22277
V161
R
M
K
Q
P
K
I
V
L
L
I
F
V
S
G
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
P28148
200
22378
V161
R
M
K
L
P
K
I
V
L
L
I
F
V
S
G
Baker's Yeast
Sacchar. cerevisiae
P13393
240
26985
V203
R
M
V
K
P
K
I
V
L
L
I
F
V
S
G
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
22.6
N.A.
86.5
N.A.
100
25.5
N.A.
48.6
96.2
92.4
78.4
26.4
21.2
41.2
25.2
30.1
Protein Similarity:
100
32.9
N.A.
88.7
N.A.
100
38.3
N.A.
49.4
97.8
95.6
90.3
40.3
35.4
51.4
35.5
44.9
P-Site Identity:
100
40
N.A.
0
N.A.
100
26.6
N.A.
0
13.3
100
73.3
40
40
60
0
40
P-Site Similarity:
100
53.3
N.A.
6.6
N.A.
100
60
N.A.
26.6
26.6
100
100
53.3
53.3
86.6
20
53.3
Percent
Protein Identity:
38.8
39
N.A.
39
30
N.A.
Protein Similarity:
58.2
58
N.A.
57
48.7
N.A.
P-Site Identity:
40
40
N.A.
40
33.3
N.A.
P-Site Similarity:
60
60
N.A.
60
53.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
6
0
0
6
0
0
23
6
0
0
6
0
6
6
0
% A
% Cys:
0
0
6
0
0
6
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
0
6
0
0
0
0
0
0
6
0
6
0
0
% E
% Phe:
6
0
0
0
0
0
0
0
0
0
0
78
0
0
0
% F
% Gly:
0
0
6
0
0
0
0
0
0
0
0
0
0
0
78
% G
% His:
0
6
0
0
0
0
6
0
0
0
0
0
0
0
6
% H
% Ile:
0
23
6
0
6
6
45
0
6
0
73
0
0
0
6
% I
% Lys:
12
6
45
28
0
28
6
0
0
17
0
0
0
0
0
% K
% Leu:
6
6
0
12
23
0
0
0
78
50
0
6
6
6
6
% L
% Met:
0
50
0
0
0
0
0
6
0
0
0
0
0
0
0
% M
% Asn:
0
0
6
12
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
6
6
0
56
6
0
0
0
0
6
6
0
0
0
% P
% Gln:
0
0
0
12
0
6
0
0
0
23
0
0
0
6
0
% Q
% Arg:
67
0
0
6
12
45
6
6
0
6
0
6
6
0
0
% R
% Ser:
0
0
0
17
0
0
6
0
6
0
0
0
28
50
0
% S
% Thr:
6
0
0
0
0
0
0
34
0
0
6
6
0
28
6
% T
% Val:
0
6
28
0
6
0
6
50
12
0
6
0
50
6
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
6
0
6
6
0
0
6
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _