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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: TBPL1 All Species: 26.67
Human Site: T59 Identified Species: 34.51
UniProt: P62380 Number Species: 17
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P62380 NP_004856.1 186 20887 T59 R K P R I T A T I W S S G K I
Chimpanzee Pan troglodytes A6H907 376 41488 L249 R E P R T T A L I F S S G K M
Rhesus Macaque Macaca mulatta
Dog Lupus familis XP_859674 165 18612 V47 Y K R D V G K V L M K L R K P
Cat Felis silvestris
Mouse Mus musculus P62340 186 20868 T59 R K P R I T A T I W S S G K I
Rat Rattus norvegicus A6H909 344 38336 L218 R E P R T T A L I F S S G K V
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001506923 368 39922 T244 R K P R I T A T I W S S G K I
Chicken Gallus gallus Q9YGV8 183 20515 T59 R K P R I T A T I W S S G K V
Frog Xenopus laevis Q9W6Z2 186 20942 T59 R K P R I T A T I W S S G K I
Zebra Danio Brachydanio rerio Q5U385 186 20743 S59 R K P R I T A S I W S S G K I
Tiger Blowfish Takifugu rubipres Q6SJ94 322 35702 L196 R E P R T T A L I F S S G K M
Fruit Fly Dros. melanogaster P20227 353 38433 L226 R E P R T T A L I F S S G K M
Honey Bee Apis mellifera XP_396371 284 32113 S110 R R P Y T T A S I W S S G K V
Nematode Worm Caenorhab. elegans P32085 340 36629 L215 R E P R T T A L I F S S G K M
Sea Urchin Strong. purpuratus P91809 265 29089 L138 R E P R T T A L I F S S G K M
Poplar Tree Populus trichocarpa XP_002325828 201 22422 L73 R E P K T T A L I F A S G K M
Maize Zea mays P50159 200 22277 L72 R E P K T T A L I F A S G K M
Rice Oryza sativa
Thale Cress Arabidopsis thaliana P28148 200 22378 L72 R E P K T T A L I F A S G K M
Baker's Yeast Sacchar. cerevisiae P13393 240 26985 L114 R E P K T T A L I F A S G K M
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 22.6 N.A. 86.5 N.A. 100 25.5 N.A. 48.6 96.2 92.4 78.4 26.4 21.2 41.2 25.2 30.1
Protein Similarity: 100 32.9 N.A. 88.7 N.A. 100 38.3 N.A. 49.4 97.8 95.6 90.3 40.3 35.4 51.4 35.5 44.9
P-Site Identity: 100 66.6 N.A. 13.3 N.A. 100 66.6 N.A. 100 93.3 100 93.3 66.6 66.6 66.6 66.6 66.6
P-Site Similarity: 100 86.6 N.A. 26.6 N.A. 100 86.6 N.A. 100 100 100 100 86.6 86.6 86.6 86.6 86.6
Percent
Protein Identity: 38.8 39 N.A. 39 30 N.A.
Protein Similarity: 58.2 58 N.A. 57 48.7 N.A.
P-Site Identity: 53.3 53.3 N.A. 53.3 53.3 N.A.
P-Site Similarity: 86.6 86.6 N.A. 86.6 86.6 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 95 0 0 0 23 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 6 0 0 0 0 0 0 0 0 0 0 0 % D
% Glu: 0 56 0 0 0 0 0 0 0 0 0 0 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 56 0 0 0 0 0 % F
% Gly: 0 0 0 0 0 6 0 0 0 0 0 0 95 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 34 0 0 0 95 0 0 0 0 0 28 % I
% Lys: 0 39 0 23 0 0 6 0 0 0 6 0 0 100 0 % K
% Leu: 0 0 0 0 0 0 0 56 6 0 0 6 0 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 6 0 0 0 0 50 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 0 0 95 0 0 0 0 0 0 0 0 0 0 0 6 % P
% Gln: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Q
% Arg: 95 6 6 67 0 0 0 0 0 0 0 0 6 0 0 % R
% Ser: 0 0 0 0 0 0 0 12 0 0 73 95 0 0 0 % S
% Thr: 0 0 0 0 62 95 0 28 0 0 0 0 0 0 0 % T
% Val: 0 0 0 0 6 0 0 6 0 0 0 0 0 0 17 % V
% Trp: 0 0 0 0 0 0 0 0 0 39 0 0 0 0 0 % W
% Tyr: 6 0 0 6 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _