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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: TBPL1 All Species: 67.88
Human Site: T69 Identified Species: 87.84
UniProt: P62380 Number Species: 17
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P62380 NP_004856.1 186 20887 T69 S S G K I I C T G A T S E E E
Chimpanzee Pan troglodytes A6H907 376 41488 T259 S S G K M V C T G A K S E E Q
Rhesus Macaque Macaca mulatta
Dog Lupus familis XP_859674 165 18612 T57 K L R K P R I T A T I W S S G
Cat Felis silvestris
Mouse Mus musculus P62340 186 20868 T69 S S G K I I C T G A T S E E E
Rat Rattus norvegicus A6H909 344 38336 T228 S S G K V V C T G A K S E D E
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001506923 368 39922 T254 S S G K I I C T G A T S E E E
Chicken Gallus gallus Q9YGV8 183 20515 T69 S S G K V I C T G A T S E E E
Frog Xenopus laevis Q9W6Z2 186 20942 T69 S S G K I I C T G A T S E E E
Zebra Danio Brachydanio rerio Q5U385 186 20743 T69 S S G K I I C T G A T S E E E
Tiger Blowfish Takifugu rubipres Q6SJ94 322 35702 T206 S S G K M V C T G A K S E E Q
Fruit Fly Dros. melanogaster P20227 353 38433 T236 S S G K M V C T G A K S E D D
Honey Bee Apis mellifera XP_396371 284 32113 T120 S S G K V T C T G A T S E V Q
Nematode Worm Caenorhab. elegans P32085 340 36629 T225 S S G K M V C T G A K S E E A
Sea Urchin Strong. purpuratus P91809 265 29089 T148 S S G K M V C T G A K R E D N
Poplar Tree Populus trichocarpa XP_002325828 201 22422 T83 A S G K M V C T G A K S E Q Q
Maize Zea mays P50159 200 22277 T82 A S G K M V C T G A K S E Q Q
Rice Oryza sativa
Thale Cress Arabidopsis thaliana P28148 200 22378 T82 A S G K M V C T G A K S E H L
Baker's Yeast Sacchar. cerevisiae P13393 240 26985 T124 A S G K M V V T G A K S E D D
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 22.6 N.A. 86.5 N.A. 100 25.5 N.A. 48.6 96.2 92.4 78.4 26.4 21.2 41.2 25.2 30.1
Protein Similarity: 100 32.9 N.A. 88.7 N.A. 100 38.3 N.A. 49.4 97.8 95.6 90.3 40.3 35.4 51.4 35.5 44.9
P-Site Identity: 100 73.3 N.A. 13.3 N.A. 100 73.3 N.A. 100 93.3 100 100 73.3 66.6 73.3 73.3 60
P-Site Similarity: 100 93.3 N.A. 13.3 N.A. 100 93.3 N.A. 100 100 100 100 93.3 93.3 86.6 86.6 80
Percent
Protein Identity: 38.8 39 N.A. 39 30 N.A.
Protein Similarity: 58.2 58 N.A. 57 48.7 N.A.
P-Site Identity: 60 60 N.A. 60 53.3 N.A.
P-Site Similarity: 93.3 93.3 N.A. 80 86.6 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 23 0 0 0 0 0 0 0 6 95 0 0 0 0 6 % A
% Cys: 0 0 0 0 0 0 89 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 0 0 0 0 0 23 12 % D
% Glu: 0 0 0 0 0 0 0 0 0 0 0 0 95 50 39 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 95 0 0 0 0 0 95 0 0 0 0 0 6 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 6 0 % H
% Ile: 0 0 0 0 28 34 6 0 0 0 6 0 0 0 0 % I
% Lys: 6 0 0 100 0 0 0 0 0 0 56 0 0 0 0 % K
% Leu: 0 6 0 0 0 0 0 0 0 0 0 0 0 0 6 % L
% Met: 0 0 0 0 50 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 6 % N
% Pro: 0 0 0 0 6 0 0 0 0 0 0 0 0 0 0 % P
% Gln: 0 0 0 0 0 0 0 0 0 0 0 0 0 12 28 % Q
% Arg: 0 0 6 0 0 6 0 0 0 0 0 6 0 0 0 % R
% Ser: 73 95 0 0 0 0 0 0 0 0 0 89 6 6 0 % S
% Thr: 0 0 0 0 0 6 0 100 0 6 39 0 0 0 0 % T
% Val: 0 0 0 0 17 56 6 0 0 0 0 0 0 6 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 6 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _