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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TBPL1
All Species:
39.09
Human Site:
Y140
Identified Species:
50.59
UniProt:
P62380
Number Species:
17
Phosphosite Substitution
Charge Score:
0.06
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P62380
NP_004856.1
186
20887
Y140
E
L
H
P
A
V
C
Y
R
I
K
S
L
R
A
Chimpanzee
Pan troglodytes
A6H907
376
41488
Y330
E
L
F
P
G
L
I
Y
R
M
I
K
P
R
I
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_859674
165
18612
F120
F
E
I
R
L
P
E
F
T
K
N
N
R
P
H
Cat
Felis silvestris
Mouse
Mus musculus
P62340
186
20868
Y140
E
L
H
P
A
V
C
Y
R
I
K
S
L
R
A
Rat
Rattus norvegicus
A6H909
344
38336
Y299
E
L
F
P
G
L
I
Y
K
M
V
K
P
Q
V
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506923
368
39922
E318
P
H
A
S
Y
E
P
E
L
H
P
A
V
C
Y
Chicken
Gallus gallus
Q9YGV8
183
20515
P136
S
Y
E
P
E
L
H
P
A
V
C
Y
R
I
K
Frog
Xenopus laevis
Q9W6Z2
186
20942
Y140
E
L
H
P
A
V
C
Y
R
I
K
S
L
R
A
Zebra Danio
Brachydanio rerio
Q5U385
186
20743
Y140
E
L
H
P
A
A
S
Y
R
I
K
N
L
R
S
Tiger Blowfish
Takifugu rubipres
Q6SJ94
322
35702
Y277
E
L
F
P
G
L
I
Y
R
M
V
K
P
R
I
Fruit Fly
Dros. melanogaster
P20227
353
38433
Y307
E
L
F
P
G
L
I
Y
R
M
V
R
P
R
I
Honey Bee
Apis mellifera
XP_396371
284
32113
Y191
E
L
H
P
G
V
T
Y
K
L
K
E
P
K
A
Nematode Worm
Caenorhab. elegans
P32085
340
36629
L290
F
S
T
Y
E
P
E
L
F
P
G
L
I
Y
R
Sea Urchin
Strong. purpuratus
P91809
265
29089
Y219
E
L
F
P
G
L
I
Y
R
M
V
K
P
R
I
Poplar Tree
Populus trichocarpa
XP_002325828
201
22422
Y154
E
I
F
P
G
L
I
Y
R
M
K
Q
P
K
I
Maize
Zea mays
P50159
200
22277
Y153
E
L
F
P
G
L
I
Y
R
M
K
Q
P
K
I
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
P28148
200
22378
Y153
E
L
F
P
G
L
I
Y
R
M
K
L
P
K
I
Baker's Yeast
Sacchar. cerevisiae
P13393
240
26985
Y195
E
L
F
P
G
L
I
Y
R
M
V
K
P
K
I
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
22.6
N.A.
86.5
N.A.
100
25.5
N.A.
48.6
96.2
92.4
78.4
26.4
21.2
41.2
25.2
30.1
Protein Similarity:
100
32.9
N.A.
88.7
N.A.
100
38.3
N.A.
49.4
97.8
95.6
90.3
40.3
35.4
51.4
35.5
44.9
P-Site Identity:
100
40
N.A.
0
N.A.
100
26.6
N.A.
0
6.6
100
73.3
40
40
53.3
0
40
P-Site Similarity:
100
53.3
N.A.
13.3
N.A.
100
53.3
N.A.
13.3
20
100
86.6
53.3
53.3
73.3
6.6
53.3
Percent
Protein Identity:
38.8
39
N.A.
39
30
N.A.
Protein Similarity:
58.2
58
N.A.
57
48.7
N.A.
P-Site Identity:
33.3
40
N.A.
40
33.3
N.A.
P-Site Similarity:
60
60
N.A.
60
53.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
6
0
23
6
0
0
6
0
0
6
0
0
23
% A
% Cys:
0
0
0
0
0
0
17
0
0
0
6
0
0
6
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
78
6
6
0
12
6
12
6
0
0
0
6
0
0
0
% E
% Phe:
12
0
50
0
0
0
0
6
6
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
56
0
0
0
0
0
6
0
0
0
0
% G
% His:
0
6
28
0
0
0
6
0
0
6
0
0
0
0
6
% H
% Ile:
0
6
6
0
0
0
50
0
0
23
6
0
6
6
45
% I
% Lys:
0
0
0
0
0
0
0
0
12
6
45
28
0
28
6
% K
% Leu:
0
73
0
0
6
56
0
6
6
6
0
12
23
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
50
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
6
12
0
0
0
% N
% Pro:
6
0
0
84
0
12
6
6
0
6
6
0
56
6
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
12
0
6
0
% Q
% Arg:
0
0
0
6
0
0
0
0
67
0
0
6
12
45
6
% R
% Ser:
6
6
0
6
0
0
6
0
0
0
0
17
0
0
6
% S
% Thr:
0
0
6
0
0
0
6
0
6
0
0
0
0
0
0
% T
% Val:
0
0
0
0
0
23
0
0
0
6
28
0
6
0
6
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
6
0
6
6
0
0
78
0
0
0
6
0
6
6
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _