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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TBPL1
All Species:
30.61
Human Site:
Y40
Identified Species:
39.61
UniProt:
P62380
Number Species:
17
Phosphosite Substitution
Charge Score:
-0.06
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P62380
NP_004856.1
186
20887
Y40
L
E
G
A
N
V
I
Y
K
R
D
V
G
K
V
Chimpanzee
Pan troglodytes
A6H907
376
41488
C213
V
S
T
V
N
L
A
C
K
L
D
L
K
K
I
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_859674
165
18612
K30
R
C
H
L
N
L
R
K
I
A
L
E
G
A
N
Cat
Felis silvestris
Mouse
Mus musculus
P62340
186
20868
Y40
L
E
G
A
N
V
I
Y
K
R
D
V
G
K
V
Rat
Rattus norvegicus
A6H909
344
38336
C182
V
S
T
A
N
L
A
C
K
L
D
L
R
K
I
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506923
368
39922
Y225
L
E
G
A
N
V
I
Y
K
R
D
V
G
K
V
Chicken
Gallus gallus
Q9YGV8
183
20515
Y40
L
E
G
A
N
V
I
Y
K
R
D
V
G
K
V
Frog
Xenopus laevis
Q9W6Z2
186
20942
Y40
L
E
G
L
N
V
I
Y
K
R
E
V
S
K
V
Zebra Danio
Brachydanio rerio
Q5U385
186
20743
Y40
L
E
G
T
N
V
I
Y
K
P
E
V
G
K
V
Tiger Blowfish
Takifugu rubipres
Q6SJ94
322
35702
S154
P
Q
L
Q
N
I
V
S
T
V
N
L
G
C
P
Fruit Fly
Dros. melanogaster
P20227
353
38433
C190
V
S
T
V
N
L
C
C
K
L
D
L
K
K
I
Honey Bee
Apis mellifera
XP_396371
284
32113
Y91
L
N
G
S
N
V
E
Y
R
R
E
N
G
M
I
Nematode Worm
Caenorhab. elegans
P32085
340
36629
V179
V
S
T
V
N
L
G
V
Q
L
D
L
K
K
I
Sea Urchin
Strong. purpuratus
P91809
265
29089
C102
V
S
T
V
N
L
N
C
R
L
D
L
K
K
I
Poplar Tree
Populus trichocarpa
XP_002325828
201
22422
Y53
L
Q
A
R
N
A
E
Y
N
P
K
R
F
A
A
Maize
Zea mays
P50159
200
22277
Y52
L
Q
A
R
N
A
E
Y
N
P
K
R
F
A
A
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
P28148
200
22378
Y52
L
Q
A
R
N
A
E
Y
N
P
K
R
F
A
A
Baker's Yeast
Sacchar. cerevisiae
P13393
240
26985
P96
A
R
N
A
E
Y
N
P
K
R
F
A
A
V
I
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
22.6
N.A.
86.5
N.A.
100
25.5
N.A.
48.6
96.2
92.4
78.4
26.4
21.2
41.2
25.2
30.1
Protein Similarity:
100
32.9
N.A.
88.7
N.A.
100
38.3
N.A.
49.4
97.8
95.6
90.3
40.3
35.4
51.4
35.5
44.9
P-Site Identity:
100
26.6
N.A.
13.3
N.A.
100
33.3
N.A.
100
100
80
80
13.3
26.6
46.6
20
20
P-Site Similarity:
100
53.3
N.A.
20
N.A.
100
60
N.A.
100
100
86.6
86.6
46.6
53.3
73.3
53.3
53.3
Percent
Protein Identity:
38.8
39
N.A.
39
30
N.A.
Protein Similarity:
58.2
58
N.A.
57
48.7
N.A.
P-Site Identity:
20
20
N.A.
20
20
N.A.
P-Site Similarity:
26.6
26.6
N.A.
26.6
26.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
6
0
17
34
0
17
12
0
0
6
0
6
6
23
17
% A
% Cys:
0
6
0
0
0
0
6
23
0
0
0
0
0
6
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
50
0
0
0
0
% D
% Glu:
0
34
0
0
6
0
23
0
0
0
17
6
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
6
0
17
0
0
% F
% Gly:
0
0
39
0
0
0
6
0
0
0
0
0
45
0
0
% G
% His:
0
0
6
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
6
34
0
6
0
0
0
0
0
39
% I
% Lys:
0
0
0
0
0
0
0
6
56
0
17
0
23
62
0
% K
% Leu:
56
0
6
12
0
34
0
0
0
28
6
34
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
6
0
% M
% Asn:
0
6
6
0
95
0
12
0
17
0
6
6
0
0
6
% N
% Pro:
6
0
0
0
0
0
0
6
0
23
0
0
0
0
6
% P
% Gln:
0
23
0
6
0
0
0
0
6
0
0
0
0
0
0
% Q
% Arg:
6
6
0
17
0
0
6
0
12
39
0
17
6
0
0
% R
% Ser:
0
28
0
6
0
0
0
6
0
0
0
0
6
0
0
% S
% Thr:
0
0
28
6
0
0
0
0
6
0
0
0
0
0
0
% T
% Val:
28
0
0
23
0
39
6
6
0
6
0
34
0
6
34
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
6
0
56
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _