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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
POLR2G
All Species:
18.18
Human Site:
S115
Identified Species:
36.36
UniProt:
P62487
Number Species:
11
Phosphosite Substitution
Charge Score:
0.27
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P62487
NP_002687.1
172
19294
S115
I
S
R
H
S
I
P
S
E
M
E
F
D
P
N
Chimpanzee
Pan troglodytes
XP_001142605
227
25089
S170
I
S
R
H
S
I
P
S
E
M
E
F
D
P
N
Rhesus Macaque
Macaca mulatta
XP_001116154
221
24489
S164
I
S
R
H
S
I
P
S
E
M
E
F
D
P
N
Dog
Lupus familis
Cat
Felis silvestris
Mouse
Mus musculus
Rat
Rattus norvegicus
P62489
172
19276
S115
I
S
R
H
S
I
P
S
E
M
E
F
D
P
N
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Q7ZW41
172
19230
S115
I
S
R
H
S
I
P
S
E
M
E
F
D
P
N
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_624976
169
18644
A111
I
S
H
H
S
I
P
A
D
M
Q
F
C
P
N
Nematode Worm
Caenorhab. elegans
NP_491093
197
22076
P138
I
S
R
H
C
I
P
P
D
M
E
F
D
P
N
Sea Urchin
Strong. purpuratus
XP_780458
172
19146
A115
I
S
R
H
S
I
P
A
D
M
E
F
D
P
N
Poplar Tree
Populus trichocarpa
XP_002298912
176
19617
D115
V
S
N
H
L
I
P
D
D
M
E
F
Q
T
G
Maize
Zea mays
NP_001149597
177
19553
D115
V
S
N
H
L
I
P
D
D
M
E
F
Q
S
G
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
P38421
176
19443
D115
V
S
K
H
L
I
P
D
D
M
E
F
Q
A
G
Baker's Yeast
Sacchar. cerevisiae
P34087
171
19040
Q117
V
T
K
H
L
M
P
Q
D
L
T
F
N
A
G
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
74.8
76.4
N.A.
N.A.
N.A.
100
N.A.
N.A.
N.A.
N.A.
98.8
N.A.
N.A.
81.4
67
92.4
Protein Similarity:
100
75.3
76.9
N.A.
N.A.
N.A.
100
N.A.
N.A.
N.A.
N.A.
100
N.A.
N.A.
91.8
77.1
98.2
P-Site Identity:
100
100
100
N.A.
N.A.
N.A.
100
N.A.
N.A.
N.A.
N.A.
100
N.A.
N.A.
66.6
80
86.6
P-Site Similarity:
100
100
100
N.A.
N.A.
N.A.
100
N.A.
N.A.
N.A.
N.A.
100
N.A.
N.A.
86.6
86.6
100
Percent
Protein Identity:
53.4
51.4
N.A.
52.2
43
N.A.
Protein Similarity:
73.3
74.5
N.A.
72.7
62.7
N.A.
P-Site Identity:
46.6
46.6
N.A.
46.6
20
N.A.
P-Site Similarity:
60
60
N.A.
66.6
66.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
17
0
0
0
0
0
17
0
% A
% Cys:
0
0
0
0
9
0
0
0
0
0
0
0
9
0
0
% C
% Asp:
0
0
0
0
0
0
0
25
59
0
0
0
59
0
0
% D
% Glu:
0
0
0
0
0
0
0
0
42
0
84
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
100
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
34
% G
% His:
0
0
9
100
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
67
0
0
0
0
92
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
17
0
0
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
0
0
0
0
34
0
0
0
0
9
0
0
0
0
0
% L
% Met:
0
0
0
0
0
9
0
0
0
92
0
0
0
0
0
% M
% Asn:
0
0
17
0
0
0
0
0
0
0
0
0
9
0
67
% N
% Pro:
0
0
0
0
0
0
100
9
0
0
0
0
0
67
0
% P
% Gln:
0
0
0
0
0
0
0
9
0
0
9
0
25
0
0
% Q
% Arg:
0
0
59
0
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
0
92
0
0
59
0
0
42
0
0
0
0
0
9
0
% S
% Thr:
0
9
0
0
0
0
0
0
0
0
9
0
0
9
0
% T
% Val:
34
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _