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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: ESRRG All Species: 26.97
Human Site: T420 Identified Species: 65.93
UniProt: P62508 Number Species: 9
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P62508 NP_001127757.1 458 51306 T420 R A G K M L M T L P L L R Q T
Chimpanzee Pan troglodytes XP_001171785 463 51709 T425 R A G K M L M T L P L L R Q T
Rhesus Macaque Macaca mulatta XP_001105251 458 51298 T420 R A G K M L M T L P L L R Q T
Dog Lupus familis XP_858408 441 49236 T403 R A G K M L M T L P L L R Q T
Cat Felis silvestris
Mouse Mus musculus Q61539 433 48383 T395 R A G K L L W T L P L L R Q T
Rat Rattus norvegicus P62510 458 51287 T420 R A G K M L M T L P L L R Q T
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001510517 462 51532 T424 R A G K M L M T L P L L R Q T
Chicken Gallus gallus P06212 589 66728 I504 R L A Q L L L I L S H I R H M
Frog Xenopus laevis P81559 586 66062 I502 R L A Q L L L I L S H I R H M
Zebra Danio Brachydanio rerio P57717 569 62828 L478 R Q A Q L L L L L S H I R H M
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 95.2 99.7 96 N.A. 72 100 N.A. 93.7 31.5 29.8 29.3 N.A. N.A. N.A. N.A. N.A.
Protein Similarity: 100 96.3 99.7 96 N.A. 83.4 100 N.A. 95.6 48 48.6 46.7 N.A. N.A. N.A. N.A. N.A.
P-Site Identity: 100 100 100 100 N.A. 86.6 100 N.A. 100 26.6 26.6 26.6 N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: 100 100 100 100 N.A. 93.3 100 N.A. 100 53.3 53.3 53.3 N.A. N.A. N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 70 30 0 0 0 0 0 0 0 0 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % D
% Glu: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 70 0 0 0 0 0 0 0 0 0 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 30 0 0 30 0 % H
% Ile: 0 0 0 0 0 0 0 20 0 0 0 30 0 0 0 % I
% Lys: 0 0 0 70 0 0 0 0 0 0 0 0 0 0 0 % K
% Leu: 0 20 0 0 40 100 30 10 100 0 70 70 0 0 0 % L
% Met: 0 0 0 0 60 0 60 0 0 0 0 0 0 0 30 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 0 0 0 0 0 0 0 0 0 70 0 0 0 0 0 % P
% Gln: 0 10 0 30 0 0 0 0 0 0 0 0 0 70 0 % Q
% Arg: 100 0 0 0 0 0 0 0 0 0 0 0 100 0 0 % R
% Ser: 0 0 0 0 0 0 0 0 0 30 0 0 0 0 0 % S
% Thr: 0 0 0 0 0 0 0 70 0 0 0 0 0 0 70 % T
% Val: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 10 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _