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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ESRRG
All Species:
22.73
Human Site:
Y250
Identified Species:
55.56
UniProt:
P62508
Number Species:
9
Phosphosite Substitution
Charge Score:
0.11
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P62508
NP_001127757.1
458
51306
Y250
V
A
E
P
E
K
I
Y
A
M
P
D
P
T
V
Chimpanzee
Pan troglodytes
XP_001171785
463
51709
Y255
V
A
E
P
E
K
I
Y
A
M
P
D
P
T
V
Rhesus Macaque
Macaca mulatta
XP_001105251
458
51298
Y250
V
A
E
P
E
K
I
Y
A
M
P
D
P
T
V
Dog
Lupus familis
XP_858408
441
49236
P238
K
I
Y
A
M
P
D
P
T
V
P
D
S
D
I
Cat
Felis silvestris
Mouse
Mus musculus
Q61539
433
48383
D236
P
N
D
I
P
E
G
D
I
K
A
L
T
T
L
Rat
Rattus norvegicus
P62510
458
51287
Y250
V
A
E
P
E
K
I
Y
A
M
P
D
P
T
V
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001510517
462
51532
Y254
V
A
E
P
E
K
I
Y
A
M
P
D
P
T
V
Chicken
Gallus gallus
P06212
589
66728
Y322
E
A
E
P
P
I
V
Y
S
E
Y
D
P
N
R
Frog
Xenopus laevis
P81559
586
66062
Y320
E
A
E
A
P
I
V
Y
S
E
H
D
S
T
K
Zebra Danio
Brachydanio rerio
P57717
569
62828
C296
G
A
E
P
P
A
V
C
S
R
Q
K
H
S
R
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
95.2
99.7
96
N.A.
72
100
N.A.
93.7
31.5
29.8
29.3
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
96.3
99.7
96
N.A.
83.4
100
N.A.
95.6
48
48.6
46.7
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
100
100
13.3
N.A.
6.6
100
N.A.
100
40
33.3
20
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
100
26.6
N.A.
26.6
100
N.A.
100
53.3
46.6
40
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
80
0
20
0
10
0
0
50
0
10
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
10
0
0
0
0
0
0
0
% C
% Asp:
0
0
10
0
0
0
10
10
0
0
0
80
0
10
0
% D
% Glu:
20
0
80
0
50
10
0
0
0
20
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
10
0
0
0
0
0
10
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
10
0
10
0
0
% H
% Ile:
0
10
0
10
0
20
50
0
10
0
0
0
0
0
10
% I
% Lys:
10
0
0
0
0
50
0
0
0
10
0
10
0
0
10
% K
% Leu:
0
0
0
0
0
0
0
0
0
0
0
10
0
0
10
% L
% Met:
0
0
0
0
10
0
0
0
0
50
0
0
0
0
0
% M
% Asn:
0
10
0
0
0
0
0
0
0
0
0
0
0
10
0
% N
% Pro:
10
0
0
70
40
10
0
10
0
0
60
0
60
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
10
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
10
0
0
0
0
20
% R
% Ser:
0
0
0
0
0
0
0
0
30
0
0
0
20
10
0
% S
% Thr:
0
0
0
0
0
0
0
0
10
0
0
0
10
70
0
% T
% Val:
50
0
0
0
0
0
30
0
0
10
0
0
0
0
50
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
10
0
0
0
0
70
0
0
10
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _