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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
RPS4X
All Species:
41.21
Human Site:
T105
Identified Species:
64.76
UniProt:
P62701
Number Species:
14
Phosphosite Substitution
Charge Score:
-0.07
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P62701
NP_000998.1
263
29598
T105
N
F
R
L
I
Y
D
T
K
G
R
F
A
V
H
Chimpanzee
Pan troglodytes
Q6GVM7
263
29340
T105
H
F
R
L
V
Y
D
T
K
G
R
F
A
V
H
Rhesus Macaque
Macaca mulatta
XP_001094914
264
29706
T106
N
F
R
L
I
Y
D
T
K
G
R
F
A
V
H
Dog
Lupus familis
XP_537399
267
29962
T105
N
F
R
L
I
Y
D
T
K
G
R
F
A
V
H
Cat
Felis silvestris
Mouse
Mus musculus
XP_897768
255
28828
T98
N
F
L
L
I
Y
D
T
K
G
R
F
A
V
H
Rat
Rattus norvegicus
NP_001103082
262
29180
T105
N
F
R
L
V
Y
D
T
K
G
R
F
A
V
H
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001510806
239
27018
K80
I
C
M
Q
R
F
I
K
I
D
G
K
V
R
T
Chicken
Gallus gallus
P47836
263
29576
T105
H
F
R
L
V
Y
D
T
K
G
R
F
A
V
H
Frog
Xenopus laevis
P49401
263
29646
T105
H
F
R
L
V
Y
D
T
K
G
R
F
A
V
H
Zebra Danio
Brachydanio rerio
Q642H9
263
29669
V105
N
F
R
L
I
Y
D
V
K
G
R
F
T
V
H
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P41042
261
29116
V102
T
G
E
F
F
R
L
V
Y
D
V
K
G
R
F
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q9N3X2
259
29025
Y102
N
E
Y
F
R
M
L
Y
D
T
K
G
R
Y
V
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
O22424
265
29999
T105
N
Y
R
L
L
Y
D
T
K
G
R
F
R
L
H
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q8VYK6
262
29797
T105
N
F
R
L
L
Y
D
T
K
G
R
F
R
L
H
Baker's Yeast
Sacchar. cerevisiae
P05753
261
29392
Y103
N
E
N
F
R
L
V
Y
D
V
K
G
R
F
A
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
93.5
98.4
97.7
N.A.
83.2
92.7
N.A.
84.7
98.4
97.3
93.1
N.A.
74.9
N.A.
63.8
N.A.
Protein Similarity:
100
96.9
99.2
98.5
N.A.
89.7
96.9
N.A.
87
99.6
99.2
97.3
N.A.
88.9
N.A.
78.3
N.A.
P-Site Identity:
100
86.6
100
100
N.A.
93.3
93.3
N.A.
0
86.6
86.6
86.6
N.A.
0
N.A.
6.6
N.A.
P-Site Similarity:
100
100
100
100
N.A.
93.3
100
N.A.
6.6
100
100
86.6
N.A.
0
N.A.
13.3
N.A.
Percent
Protein Identity:
N.A.
69.4
N.A.
69.5
71.8
N.A.
Protein Similarity:
N.A.
82.2
N.A.
82.5
84.7
N.A.
P-Site Identity:
N.A.
73.3
N.A.
80
6.6
N.A.
P-Site Similarity:
N.A.
93.3
N.A.
93.3
13.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
0
0
0
0
54
0
7
% A
% Cys:
0
7
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
74
0
14
14
0
0
0
0
0
% D
% Glu:
0
14
7
0
0
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
67
0
20
7
7
0
0
0
0
0
74
0
7
7
% F
% Gly:
0
7
0
0
0
0
0
0
0
74
7
14
7
0
0
% G
% His:
20
0
0
0
0
0
0
0
0
0
0
0
0
0
74
% H
% Ile:
7
0
0
0
34
0
7
0
7
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
0
0
7
74
0
14
14
0
0
0
% K
% Leu:
0
0
7
74
14
7
14
0
0
0
0
0
0
14
0
% L
% Met:
0
0
7
0
0
7
0
0
0
0
0
0
0
0
0
% M
% Asn:
67
0
7
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
7
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
67
0
20
7
0
0
0
0
74
0
27
14
0
% R
% Ser:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% S
% Thr:
7
0
0
0
0
0
0
67
0
7
0
0
7
0
7
% T
% Val:
0
0
0
0
27
0
7
14
0
7
7
0
7
60
7
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
7
7
0
0
74
0
14
7
0
0
0
0
7
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _