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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: ACTA2 All Species: 35.76
Human Site: S157 Identified Species: 98.33
UniProt: P62736 Number Species: 8
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P62736 NP_001135417.1 377 42009 S157 T T G I V L D S G D G V T H N
Chimpanzee Pan troglodytes
Rhesus Macaque Macaca mulatta
Dog Lupus familis
Cat Felis silvestris
Mouse Mus musculus
Rat Rattus norvegicus P62738 377 41990 S157 T T G I V L D S G D G V T H N
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001506759 377 42004 S157 T T G I V L D S G D G V T H N
Chicken Gallus gallus P08023 377 41976 S157 T T G I V L D S G D G V T H N
Frog Xenopus laevis P04751 377 41997 S157 T T G I V L D S G D G V T H N
Zebra Danio Brachydanio rerio NP_997785 377 42037 S157 T T G I V L D S G D G V T H N
Tiger Blowfish Takifugu rubipres P53482 377 41958 S157 T T G I V L D S G D G V T H N
Fruit Fly Dros. melanogaster P10987 376 41803 S156 T T G I V L D S G D G V S H T
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans P10984 376 41759 S156 T T G I V L D S G D G V T H T
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 N.A. N.A. N.A. N.A. N.A. 100 N.A. 99.7 99.7 98.1 98.9 98.1 94.1 N.A. 94.4 N.A.
Protein Similarity: 100 N.A. N.A. N.A. N.A. N.A. 100 N.A. 100 100 99.4 99.7 99.4 96.8 N.A. 97 N.A.
P-Site Identity: 100 N.A. N.A. N.A. N.A. N.A. 100 N.A. 100 100 100 100 100 86.6 N.A. 93.3 N.A.
P-Site Similarity: 100 N.A. N.A. N.A. N.A. N.A. 100 N.A. 100 100 100 100 100 93.3 N.A. 93.3 N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 100 0 0 100 0 0 0 0 0 % D
% Glu: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 100 0 0 0 0 0 100 0 100 0 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 100 0 % H
% Ile: 0 0 0 100 0 0 0 0 0 0 0 0 0 0 0 % I
% Lys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % K
% Leu: 0 0 0 0 0 100 0 0 0 0 0 0 0 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 78 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % P
% Gln: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Q
% Arg: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % R
% Ser: 0 0 0 0 0 0 0 100 0 0 0 0 12 0 0 % S
% Thr: 100 100 0 0 0 0 0 0 0 0 0 0 89 0 23 % T
% Val: 0 0 0 0 100 0 0 0 0 0 0 100 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _