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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ACTA2
All Species:
36.36
Human Site:
S283
Identified Species:
100
UniProt:
P62736
Number Species:
8
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P62736
NP_001135417.1
377
42009
S283
I
H
E
T
T
Y
N
S
I
M
K
C
D
I
D
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
Cat
Felis silvestris
Mouse
Mus musculus
Rat
Rattus norvegicus
P62738
377
41990
S283
I
H
E
T
T
Y
N
S
I
M
K
C
D
I
D
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506759
377
42004
S283
I
H
E
T
T
Y
N
S
I
M
K
C
D
I
D
Chicken
Gallus gallus
P08023
377
41976
S283
I
H
E
T
T
Y
N
S
I
M
K
C
D
I
D
Frog
Xenopus laevis
P04751
377
41997
S283
I
H
E
T
T
Y
N
S
I
M
K
C
D
I
D
Zebra Danio
Brachydanio rerio
NP_997785
377
42037
S283
I
H
E
T
T
Y
N
S
I
M
K
C
D
I
D
Tiger Blowfish
Takifugu rubipres
P53482
377
41958
S283
I
H
E
T
T
Y
N
S
I
M
K
C
D
I
D
Fruit Fly
Dros. melanogaster
P10987
376
41803
S282
I
H
E
T
T
Y
N
S
I
M
K
C
D
V
D
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
P10984
376
41759
S282
I
H
E
T
S
Y
N
S
I
M
K
C
D
I
D
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
N.A.
N.A.
N.A.
N.A.
100
N.A.
99.7
99.7
98.1
98.9
98.1
94.1
N.A.
94.4
N.A.
Protein Similarity:
100
N.A.
N.A.
N.A.
N.A.
N.A.
100
N.A.
100
100
99.4
99.7
99.4
96.8
N.A.
97
N.A.
P-Site Identity:
100
N.A.
N.A.
N.A.
N.A.
N.A.
100
N.A.
100
100
100
100
100
93.3
N.A.
93.3
N.A.
P-Site Similarity:
100
N.A.
N.A.
N.A.
N.A.
N.A.
100
N.A.
100
100
100
100
100
100
N.A.
100
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
100
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
0
100
0
100
% D
% Glu:
0
0
100
0
0
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
100
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
100
0
0
0
0
0
0
0
100
0
0
0
0
89
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
100
0
0
0
0
% K
% Leu:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
100
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
100
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
0
0
0
0
12
0
0
100
0
0
0
0
0
0
0
% S
% Thr:
0
0
0
100
89
0
0
0
0
0
0
0
0
0
0
% T
% Val:
0
0
0
0
0
0
0
0
0
0
0
0
0
12
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
100
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _