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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: RPS6 All Species: 46.97
Human Site: T10 Identified Species: 73.81
UniProt: P62753 Number Species: 14
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P62753 NP_001001.2 249 28681 T10 L N I S F P A T G C Q K L I E
Chimpanzee Pan troglodytes XP_001147795 323 36940 T91 L N I S F P A T G C Q K L I E
Rhesus Macaque Macaca mulatta XP_001109154 222 25518
Dog Lupus familis XP_533921 249 28564 T10 L N I S F P A T G C Q K L I E
Cat Felis silvestris
Mouse Mus musculus NP_033122 249 28662 T10 L N I S F P A T G C Q K L I E
Rat Rattus norvegicus P62755 249 28662 T10 L N I S F P A T G C Q K L I E
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001506325 213 24331
Chicken Gallus gallus P47838 249 28636 T10 L N I S F P A T G C Q K L I E
Frog Xenopus laevis P39017 249 28658 T10 L N I S F P A T G C Q K L I E
Zebra Danio Brachydanio rerio NP_001003728 249 28690 T10 L N I S F P A T G C Q K L I E
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P29327 248 28389 T10 L N V S Y P A T G C Q K L F E
Honey Bee Apis mellifera XP_001120419 251 28877 T10 L N V S Y P A T G C Q K L F E
Nematode Worm Caenorhab. elegans Q9NEN6 246 28117 T10 L N F A Y P A T G L Q K S F E
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana P51430 249 28143 T10 F N V A N P T T G C Q K K L E
Baker's Yeast Sacchar. cerevisiae P02365 236 26978 N10 L N I S Y P V N G S Q K T F E
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 74.9 88.3 98.8 N.A. 100 100 N.A. 82.3 97.9 96.3 95.5 N.A. 75 76 59.4 N.A.
Protein Similarity: 100 74.9 89.1 99.1 N.A. 100 100 N.A. 83.9 99.5 98.3 97.9 N.A. 85.9 88 76.3 N.A.
P-Site Identity: 100 100 0 100 N.A. 100 100 N.A. 0 100 100 100 N.A. 80 80 60 N.A.
P-Site Similarity: 100 100 0 100 N.A. 100 100 N.A. 0 100 100 100 N.A. 93.3 93.3 73.3 N.A.
Percent
Protein Identity: N.A. N.A. N.A. 63.8 60.6 N.A.
Protein Similarity: N.A. N.A. N.A. 78.3 76.3 N.A.
P-Site Identity: N.A. N.A. N.A. 53.3 60 N.A.
P-Site Similarity: N.A. N.A. N.A. 73.3 66.6 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 14 0 0 74 0 0 0 0 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 74 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % D
% Glu: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 87 % E
% Phe: 7 0 7 0 54 0 0 0 0 0 0 0 0 27 0 % F
% Gly: 0 0 0 0 0 0 0 0 87 0 0 0 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 60 0 0 0 0 0 0 0 0 0 0 54 0 % I
% Lys: 0 0 0 0 0 0 0 0 0 0 0 87 7 0 0 % K
% Leu: 80 0 0 0 0 0 0 0 0 7 0 0 67 7 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 87 0 0 7 0 0 7 0 0 0 0 0 0 0 % N
% Pro: 0 0 0 0 0 87 0 0 0 0 0 0 0 0 0 % P
% Gln: 0 0 0 0 0 0 0 0 0 0 87 0 0 0 0 % Q
% Arg: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % R
% Ser: 0 0 0 74 0 0 0 0 0 7 0 0 7 0 0 % S
% Thr: 0 0 0 0 0 0 7 80 0 0 0 0 7 0 0 % T
% Val: 0 0 20 0 0 0 7 0 0 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 27 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _