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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
RPS6
All Species:
34.24
Human Site:
T181
Identified Species:
53.81
UniProt:
P62753
Number Species:
14
Phosphosite Substitution
Charge Score:
-0.14
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P62753
NP_001001.2
249
28681
T181
P
K
I
Q
R
L
V
T
P
R
V
L
Q
H
K
Chimpanzee
Pan troglodytes
XP_001147795
323
36940
K262
T
P
R
V
L
Q
H
K
R
R
R
I
A
L
K
Rhesus Macaque
Macaca mulatta
XP_001109154
222
25518
P169
L
N
K
E
G
K
K
P
R
T
K
A
P
K
I
Dog
Lupus familis
XP_533921
249
28564
T181
P
K
I
Q
R
L
V
T
P
R
V
L
Q
H
K
Cat
Felis silvestris
Mouse
Mus musculus
NP_033122
249
28662
T181
P
K
I
Q
R
L
V
T
P
R
V
L
Q
H
K
Rat
Rattus norvegicus
P62755
249
28662
T181
P
K
I
Q
R
L
V
T
P
R
V
L
Q
H
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506325
213
24331
K160
R
R
R
I
A
L
K
K
Q
R
T
Q
K
N
K
Chicken
Gallus gallus
P47838
249
28636
T181
P
K
I
Q
R
L
V
T
P
R
V
L
Q
H
K
Frog
Xenopus laevis
P39017
249
28658
T181
P
K
I
Q
R
L
V
T
P
R
V
L
Q
H
K
Zebra Danio
Brachydanio rerio
NP_001003728
249
28690
T181
P
K
I
Q
R
L
V
T
P
R
V
L
Q
H
K
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P29327
248
28389
I181
A
P
K
I
Q
R
L
I
T
P
V
V
L
Q
R
Honey Bee
Apis mellifera
XP_001120419
251
28877
T181
P
K
I
Q
R
L
I
T
P
L
T
L
Q
R
K
Nematode Worm
Caenorhab. elegans
Q9NEN6
246
28117
T181
P
K
I
Q
R
L
I
T
P
A
R
I
A
R
K
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
P51430
249
28143
L183
K
A
P
K
I
Q
R
L
V
T
P
L
T
L
Q
Baker's Yeast
Sacchar. cerevisiae
P02365
236
26978
P181
K
I
Q
R
L
V
T
P
Q
R
L
Q
R
K
R
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
74.9
88.3
98.8
N.A.
100
100
N.A.
82.3
97.9
96.3
95.5
N.A.
75
76
59.4
N.A.
Protein Similarity:
100
74.9
89.1
99.1
N.A.
100
100
N.A.
83.9
99.5
98.3
97.9
N.A.
85.9
88
76.3
N.A.
P-Site Identity:
100
13.3
0
100
N.A.
100
100
N.A.
20
100
100
100
N.A.
6.6
73.3
60
N.A.
P-Site Similarity:
100
20
6.6
100
N.A.
100
100
N.A.
40
100
100
100
N.A.
33.3
80
73.3
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
63.8
60.6
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
78.3
76.3
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
6.6
6.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
20
40
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
7
7
0
0
7
0
0
0
0
7
0
7
14
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
0
7
0
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
7
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
7
0
0
0
0
0
0
47
0
% H
% Ile:
0
7
60
14
7
0
14
7
0
0
0
14
0
0
7
% I
% Lys:
14
60
14
7
0
7
14
14
0
0
7
0
7
14
74
% K
% Leu:
7
0
0
0
14
67
7
7
0
7
7
60
7
14
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
7
0
0
0
0
0
0
0
0
0
0
0
7
0
% N
% Pro:
60
14
7
0
0
0
0
14
60
7
7
0
7
0
0
% P
% Gln:
0
0
7
60
7
14
0
0
14
0
0
14
54
7
7
% Q
% Arg:
7
7
14
7
60
7
7
0
14
67
14
0
7
14
14
% R
% Ser:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% S
% Thr:
7
0
0
0
0
0
7
60
7
14
14
0
7
0
0
% T
% Val:
0
0
0
7
0
7
47
0
7
0
54
7
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _