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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: RAN All Species: 63.64
Human Site: Y147 Identified Species: 100
UniProt: P62826 Number Species: 14
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P62826 NP_006316.1 216 24423 Y147 R K K N L Q Y Y D I S A K S N
Chimpanzee Pan troglodytes XP_509522 236 26391 Y167 R K K N L Q Y Y D I S A K S N
Rhesus Macaque Macaca mulatta
Dog Lupus familis XP_854554 230 25721 Y161 R K K N L Q Y Y D I S A K S N
Cat Felis silvestris
Mouse Mus musculus Q61820 216 24434 Y147 R K K N L Q Y Y D I S A R S N
Rat Rattus norvegicus P62828 216 24405 Y147 R K K N L Q Y Y D I S A K S N
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus P42558 216 24409 Y147 R K K N L Q Y Y D I S A K S N
Frog Xenopus laevis P52301 216 24380 Y147 R K K N L Q Y Y D I S A K S N
Zebra Danio Brachydanio rerio P79735 215 24442 Y146 R K K N L Q Y Y D I S A K S N
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9VZ23 216 24690 Y147 R K K N L Q Y Y D I S A K S N
Honey Bee Apis mellifera XP_393761 215 24626 Y146 R K K N L Q Y Y D I S A K S N
Nematode Worm Caenorhab. elegans O17915 215 24235 Y146 R K K N L Q Y Y D I S A K S N
Sea Urchin Strong. purpuratus XP_786730 224 25572 Y155 R K K N L Q Y Y D I S A K S N
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q8H156 221 25061 Y150 R K K N L Q Y Y E I S A K S N
Baker's Yeast Sacchar. cerevisiae P32836 220 24972 Y150 R K K N L Q Y Y D I S A K S N
Red Bread Mold Neurospora crassa Q7RVL0 215 24257 Y144 R K K N L Q Y Y D I S A K S N
Conservation
Percent
Protein Identity: 100 91.5 N.A. 87.8 N.A. 93.9 100 N.A. N.A. 98.6 98.1 94.4 N.A. 87 87.5 86.5 80.8
Protein Similarity: 100 91.5 N.A. 90 N.A. 98.1 100 N.A. N.A. 99.5 98.6 96.3 N.A. 91.6 91.6 91.6 87.5
P-Site Identity: 100 100 N.A. 100 N.A. 93.3 100 N.A. N.A. 100 100 100 N.A. 100 100 100 100
P-Site Similarity: 100 100 N.A. 100 N.A. 100 100 N.A. N.A. 100 100 100 N.A. 100 100 100 100
Percent
Protein Identity: N.A. N.A. N.A. 73.3 80.9 78.7
Protein Similarity: N.A. N.A. N.A. 81 87.7 85.6
P-Site Identity: N.A. N.A. N.A. 93.3 100 100
P-Site Similarity: N.A. N.A. N.A. 100 100 100
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 0 0 0 0 0 100 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 94 0 0 0 0 0 0 % D
% Glu: 0 0 0 0 0 0 0 0 7 0 0 0 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 0 100 0 0 0 0 0 % I
% Lys: 0 100 100 0 0 0 0 0 0 0 0 0 94 0 0 % K
% Leu: 0 0 0 0 100 0 0 0 0 0 0 0 0 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 100 0 0 0 0 0 0 0 0 0 0 100 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % P
% Gln: 0 0 0 0 0 100 0 0 0 0 0 0 0 0 0 % Q
% Arg: 100 0 0 0 0 0 0 0 0 0 0 0 7 0 0 % R
% Ser: 0 0 0 0 0 0 0 0 0 0 100 0 0 100 0 % S
% Thr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % T
% Val: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 100 100 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _