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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: RPS25 All Species: 44.24
Human Site: Y65 Identified Species: 64.89
UniProt: P62851 Number Species: 15
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P62851 NP_001019.1 125 13742 Y65 L C K E V P N Y K L I T P A V
Chimpanzee Pan troglodytes XP_001149453 125 13784 Y65 L C K E V P N Y K L I T P A V
Rhesus Macaque Macaca mulatta XP_001115457 125 13714 Y65 L C K E V P N Y K L I T P A V
Dog Lupus familis XP_536549 199 21299 Y139 L C K E V P N Y K L I T P A V
Cat Felis silvestris
Mouse Mus musculus XP_001475303 125 13739 Y65 L C K E V L N Y K L I T P A V
Rat Rattus norvegicus XP_001060586 125 13754 Y65 L C K E V P N Y K L I T P A V
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001511033 125 13724 Y65 L C K E V P N Y K L I T P A V
Chicken Gallus gallus XP_001234052 125 13694 Y65 L C K E V P N Y K L I T P A V
Frog Xenopus laevis
Zebra Danio Brachydanio rerio Q6PBI5 124 13842 Y64 L Y K E V P N Y K L I T P A V
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P48588 117 13183 K59 A T Y E K L Y K E V P A Y K L
Honey Bee Apis mellifera XP_001119888 119 13417 Y64 L L K E V P Q Y K L I T P S I
Nematode Worm Caenorhab. elegans P52821 117 12894 Y61 L Y K E V I T Y K L I T P S V
Sea Urchin Strong. purpuratus XP_001177501 112 12611 V56 Y E K L Y K E V P T Y K L I T
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q8GYL5 108 12000 S53 A T Y D K L L S E A P K F K L
Baker's Yeast Sacchar. cerevisiae Q3E792 108 12021 E53 K Y D R I L K E V P T Y R Y V
Red Bread Mold Neurospora crassa Q7SC06 97 10779 V42 S D K L Y K D V Q S Y R L V T
Conservation
Percent
Protein Identity: 100 98.4 99.1 62.8 N.A. 98.4 98.4 N.A. 98.4 99.1 N.A. 90.4 N.A. 68 68 62.4 72.8
Protein Similarity: 100 98.4 99.1 62.8 N.A. 99.1 99.1 N.A. 99.1 99.1 N.A. 92.8 N.A. 72.8 74.4 71.1 78.4
P-Site Identity: 100 100 100 100 N.A. 93.3 100 N.A. 100 100 N.A. 93.3 N.A. 6.6 73.3 73.3 6.6
P-Site Similarity: 100 100 100 100 N.A. 93.3 100 N.A. 100 100 N.A. 93.3 N.A. 26.6 86.6 80 6.6
Percent
Protein Identity: N.A. N.A. N.A. 51.2 43.2 43.2
Protein Similarity: N.A. N.A. N.A. 65.6 60 53.6
P-Site Identity: N.A. N.A. N.A. 0 6.6 6.6
P-Site Similarity: N.A. N.A. N.A. 20 13.3 20
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 13 0 0 0 0 0 0 0 0 7 0 7 0 57 0 % A
% Cys: 0 50 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 7 7 7 0 0 7 0 0 0 0 0 0 0 0 % D
% Glu: 0 7 0 75 0 0 7 7 13 0 0 0 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 7 0 0 % F
% Gly: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 7 7 0 0 0 0 69 0 0 7 7 % I
% Lys: 7 0 82 0 13 13 7 7 69 0 0 13 0 13 0 % K
% Leu: 69 7 0 13 0 25 7 0 0 69 0 0 13 0 13 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 57 0 0 0 0 0 0 0 0 % N
% Pro: 0 0 0 0 0 57 0 0 7 7 13 0 69 0 0 % P
% Gln: 0 0 0 0 0 0 7 0 7 0 0 0 0 0 0 % Q
% Arg: 0 0 0 7 0 0 0 0 0 0 0 7 7 0 0 % R
% Ser: 7 0 0 0 0 0 0 7 0 7 0 0 0 13 0 % S
% Thr: 0 13 0 0 0 0 7 0 0 7 7 69 0 0 13 % T
% Val: 0 0 0 0 69 0 0 13 7 7 0 0 0 7 69 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 7 19 13 0 13 0 7 69 0 0 13 7 7 7 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _