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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: GNB1 All Species: 61.21
Human Site: S74 Identified Species: 89.78
UniProt: P62873 Number Species: 15
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P62873 NP_002065.1 340 37377 S74 S R L L V S A S Q D G K L I I
Chimpanzee Pan troglodytes XP_524842 338 37260 S72 T D S R L L V S A S Q D G K L
Rhesus Macaque Macaca mulatta
Dog Lupus familis XP_545211 340 37563 S74 S R L L V S A S Q D G K L I I
Cat Felis silvestris
Mouse Mus musculus P29387 340 37361 S74 S R L L V S A S Q D G K L I I
Rat Rattus norvegicus O35353 340 37345 S74 S R L L V S A S Q D G K L I I
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001508337 967 105634 S701 S R L L V S A S Q D G K L I I
Chicken Gallus gallus NP_001012853 404 44596 S74 S R L L V S A S Q D G K L I I
Frog Xenopus laevis P79959 340 37311 S74 S R L L V S A S Q D G K L I I
Zebra Danio Brachydanio rerio Q6PH57 340 37267 S74 S R L L V S A S Q D G K L I I
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P26308 340 37114 S74 S R N L V S A S Q D G K L I V
Honey Bee Apis mellifera XP_393976 341 37351 S75 S R N L V S A S Q D G K L I V
Nematode Worm Caenorhab. elegans P17343 340 37388 S74 S R N L V S A S Q D G K L I V
Sea Urchin Strong. purpuratus XP_001176793 341 37543 S75 S R N L V S A S Q D G K L I V
Poplar Tree Populus trichocarpa
Maize Zea mays P49178 380 41696 S85 K N W I V S A S Q D G R L I V
Rice Oryza sativa
Thale Cress Arabidopsis thaliana P49177 377 40987 S84 R N R I V S A S Q D G R L I V
Baker's Yeast Sacchar. cerevisiae P18851 423 46563 S111 S K R I L S A S Q D G F M L I
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 92.6 N.A. 90.8 N.A. 89.7 90 N.A. 34.7 80.9 97.3 98.8 N.A. 83.5 85.9 85.8 87.1
Protein Similarity: 100 95.5 N.A. 95.8 N.A. 95.8 95.8 N.A. 35 81.9 98.5 99.1 N.A. 91.7 93.2 94.1 93.8
P-Site Identity: 100 6.6 N.A. 100 N.A. 100 100 N.A. 100 100 100 100 N.A. 86.6 86.6 86.6 86.6
P-Site Similarity: 100 26.6 N.A. 100 N.A. 100 100 N.A. 100 100 100 100 N.A. 93.3 93.3 93.3 93.3
Percent
Protein Identity: N.A. 43.6 N.A. 44 33.3 N.A.
Protein Similarity: N.A. 63.1 N.A. 62.3 51.3 N.A.
P-Site Identity: N.A. 60 N.A. 60 53.3 N.A.
P-Site Similarity: N.A. 80 N.A. 80 86.6 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 94 0 7 0 0 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 7 0 0 0 0 0 0 0 94 0 7 0 0 0 % D
% Glu: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 7 0 0 0 % F
% Gly: 0 0 0 0 0 0 0 0 0 0 94 0 7 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 19 0 0 0 0 0 0 0 0 0 88 57 % I
% Lys: 7 7 0 0 0 0 0 0 0 0 0 75 0 7 0 % K
% Leu: 0 0 50 75 13 7 0 0 0 0 0 0 88 7 7 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 7 0 0 % M
% Asn: 0 13 25 0 0 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % P
% Gln: 0 0 0 0 0 0 0 0 94 0 7 0 0 0 0 % Q
% Arg: 7 75 13 7 0 0 0 0 0 0 0 13 0 0 0 % R
% Ser: 82 0 7 0 0 94 0 100 0 7 0 0 0 0 0 % S
% Thr: 7 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % T
% Val: 0 0 0 0 88 0 7 0 0 0 0 0 0 0 38 % V
% Trp: 0 0 7 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _