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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
GNB1
All Species:
62.42
Human Site:
T249
Identified Species:
91.56
UniProt:
P62873
Number Species:
15
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P62873
NP_002065.1
340
37377
T249
A
T
G
S
D
D
A
T
C
R
L
F
D
L
R
Chimpanzee
Pan troglodytes
XP_524842
338
37260
T247
A
T
G
S
D
D
A
T
C
R
L
F
D
L
R
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_545211
340
37563
T249
A
T
G
S
D
D
A
T
C
R
L
F
D
L
R
Cat
Felis silvestris
Mouse
Mus musculus
P29387
340
37361
T249
A
T
G
S
D
D
A
T
C
R
L
F
D
L
R
Rat
Rattus norvegicus
O35353
340
37345
T249
A
T
G
S
D
D
A
T
C
R
L
F
D
L
R
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001508337
967
105634
T876
A
T
G
S
D
D
A
T
C
R
L
F
D
L
R
Chicken
Gallus gallus
NP_001012853
404
44596
T249
A
T
G
S
D
D
A
T
C
R
L
F
D
L
R
Frog
Xenopus laevis
P79959
340
37311
T249
A
T
G
S
D
D
A
T
C
R
L
F
D
L
R
Zebra Danio
Brachydanio rerio
Q6PH57
340
37267
T249
A
T
G
S
D
D
A
T
C
R
L
F
D
L
R
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P26308
340
37114
T249
A
T
G
S
D
D
A
T
C
R
L
F
D
I
R
Honey Bee
Apis mellifera
XP_393976
341
37351
T250
A
T
G
S
D
D
A
T
C
R
L
F
D
I
R
Nematode Worm
Caenorhab. elegans
P17343
340
37388
T249
A
T
G
S
D
D
A
T
C
R
L
F
D
I
R
Sea Urchin
Strong. purpuratus
XP_001176793
341
37543
T250
A
T
G
S
D
D
A
T
C
R
L
F
D
I
R
Poplar Tree
Populus trichocarpa
Maize
Zea mays
P49178
380
41696
T272
G
T
G
S
D
D
G
T
C
R
L
F
D
M
R
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
P49177
377
40987
T271
G
T
G
S
D
D
G
T
C
R
L
Y
D
I
R
Baker's Yeast
Sacchar. cerevisiae
P18851
423
46563
A293
V
A
G
S
D
N
G
A
I
N
M
Y
D
L
R
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
92.6
N.A.
90.8
N.A.
89.7
90
N.A.
34.7
80.9
97.3
98.8
N.A.
83.5
85.9
85.8
87.1
Protein Similarity:
100
95.5
N.A.
95.8
N.A.
95.8
95.8
N.A.
35
81.9
98.5
99.1
N.A.
91.7
93.2
94.1
93.8
P-Site Identity:
100
100
N.A.
100
N.A.
100
100
N.A.
100
100
100
100
N.A.
93.3
93.3
93.3
93.3
P-Site Similarity:
100
100
N.A.
100
N.A.
100
100
N.A.
100
100
100
100
N.A.
100
100
100
100
Percent
Protein Identity:
N.A.
43.6
N.A.
44
33.3
N.A.
Protein Similarity:
N.A.
63.1
N.A.
62.3
51.3
N.A.
P-Site Identity:
N.A.
80
N.A.
73.3
40
N.A.
P-Site Similarity:
N.A.
86.6
N.A.
86.6
60
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
82
7
0
0
0
0
82
7
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
94
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
100
94
0
0
0
0
0
0
100
0
0
% D
% Glu:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
88
0
0
0
% F
% Gly:
13
0
100
0
0
0
19
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
7
0
0
0
0
32
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
0
0
0
0
0
0
0
0
0
0
94
0
0
63
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
7
0
0
7
0
% M
% Asn:
0
0
0
0
0
7
0
0
0
7
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
94
0
0
0
0
100
% R
% Ser:
0
0
0
100
0
0
0
0
0
0
0
0
0
0
0
% S
% Thr:
0
94
0
0
0
0
0
94
0
0
0
0
0
0
0
% T
% Val:
7
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
13
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _