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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
POLR2L
All Species:
42.42
Human Site:
Y21
Identified Species:
93.33
UniProt:
P62875
Number Species:
10
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P62875
NP_066951.1
67
7645
Y21
V
G
N
K
W
E
A
Y
L
G
L
L
Q
A
E
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
Cat
Felis silvestris
Mouse
Mus musculus
XP_001480836
67
7626
Y21
V
G
N
K
W
E
A
Y
L
G
L
L
Q
A
K
Rat
Rattus norvegicus
XP_002728623
67
7564
Y21
V
G
N
K
W
E
A
Y
L
G
L
L
Q
A
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_001153297
67
7643
Y21
V
G
N
K
W
E
A
Y
L
G
L
L
Q
A
E
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VC49
67
7643
Y21
I
G
N
K
W
E
S
Y
L
G
L
L
Q
A
E
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q9GR61
67
7802
Y21
I
G
D
K
W
E
T
Y
L
G
F
L
Q
S
E
Sea Urchin
Strong. purpuratus
XP_790633
67
7599
Y21
V
G
N
K
W
E
A
Y
L
G
L
L
Q
A
E
Poplar Tree
Populus trichocarpa
XP_002326311
71
8113
Y21
I
G
N
K
W
D
T
Y
L
D
L
L
Q
A
D
Maize
Zea mays
NP_001148175
242
27752
Y192
I
G
N
K
W
D
L
Y
L
D
L
L
Q
A
D
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9SYA6
71
8154
Y21
I
G
N
K
W
D
T
Y
L
E
L
L
Q
A
D
Baker's Yeast
Sacchar. cerevisiae
P22139
70
8259
Y21
V
G
D
K
W
E
S
Y
L
N
L
L
Q
E
D
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
N.A.
N.A.
N.A.
98.5
95.5
N.A.
N.A.
N.A.
N.A.
98.5
N.A.
92.5
N.A.
85
97
Protein Similarity:
100
N.A.
N.A.
N.A.
N.A.
100
97
N.A.
N.A.
N.A.
N.A.
100
N.A.
98.5
N.A.
95.5
100
P-Site Identity:
100
N.A.
N.A.
N.A.
N.A.
93.3
100
N.A.
N.A.
N.A.
N.A.
100
N.A.
86.6
N.A.
66.6
100
P-Site Similarity:
100
N.A.
N.A.
N.A.
N.A.
100
100
N.A.
N.A.
N.A.
N.A.
100
N.A.
100
N.A.
86.6
100
Percent
Protein Identity:
78.8
22.3
N.A.
74.6
71.4
N.A.
Protein Similarity:
85.9
24.7
N.A.
84.5
80
N.A.
P-Site Identity:
66.6
66.6
N.A.
66.6
66.6
N.A.
P-Site Similarity:
86.6
86.6
N.A.
86.6
86.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
46
0
0
0
0
0
0
82
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
19
0
0
28
0
0
0
19
0
0
0
0
37
% D
% Glu:
0
0
0
0
0
73
0
0
0
10
0
0
0
10
55
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
10
0
0
0
0
% F
% Gly:
0
100
0
0
0
0
0
0
0
64
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
46
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
100
0
0
0
0
0
0
0
0
0
0
10
% K
% Leu:
0
0
0
0
0
0
10
0
100
0
91
100
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
82
0
0
0
0
0
0
10
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
100
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
0
0
0
0
0
0
19
0
0
0
0
0
0
10
0
% S
% Thr:
0
0
0
0
0
0
28
0
0
0
0
0
0
0
0
% T
% Val:
55
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
100
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
100
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _