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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: FKBP1A All Species: 39.39
Human Site: T22 Identified Species: 72.22
UniProt: P62942 Number Species: 12
    Phosphosite Substitution
    Charge Score: -0.08
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P62942 NP_000792.1 108 11951 T22 T F P K R G Q T C V V H Y T G
Chimpanzee Pan troglodytes XP_001167897 150 16282 T64 T F P K R G Q T C V V H Y T G
Rhesus Macaque Macaca mulatta XP_001108820 181 19339 T95 T F P K R G Q T C V V H Y T G
Dog Lupus familis XP_851390 109 12008 T23 T F P K R G Q T C V V H Y T G
Cat Felis silvestris
Mouse Mus musculus P26883 108 11904 T22 T F P K R G Q T C V V H Y T G
Rat Rattus norvegicus Q62658 108 11904 T22 T F P K R G Q T C V V H Y T G
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus NP_989661 108 11954 T22 T F P K R G Q T C V V H Y T G
Frog Xenopus laevis O42123 108 11893 T22 T F P K K G Q T V V V H Y V G
Zebra Danio Brachydanio rerio NP_957106 108 11875 T22 T F P K K G Q T C V V H Y I G
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P48375 108 11648 K22 T Y P K N G Q K V T V H Y T G
Honey Bee Apis mellifera XP_624498 109 11746 T22 T Y P K T G Q T V V V H Y T G
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae P20081 114 12139 L28 T F P K T G D L V T I H Y T G
Red Bread Mold Neurospora crassa P20080 120 13018 N28 R E T R R G D N V D V H Y K G
Conservation
Percent
Protein Identity: 100 72 59.6 98.1 N.A. 97.2 97.2 N.A. N.A. 91.6 84.2 84.2 N.A. 75.9 70.6 N.A. N.A.
Protein Similarity: 100 72 59.6 99 N.A. 97.2 97.2 N.A. N.A. 99 93.5 96.3 N.A. 86.1 87.1 N.A. N.A.
P-Site Identity: 100 100 100 100 N.A. 100 100 N.A. N.A. 100 80 86.6 N.A. 66.6 80 N.A. N.A.
P-Site Similarity: 100 100 100 100 N.A. 100 100 N.A. N.A. 100 86.6 93.3 N.A. 73.3 86.6 N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. 55.2 41.6
Protein Similarity: N.A. N.A. N.A. N.A. 73.6 62.5
P-Site Identity: N.A. N.A. N.A. N.A. 60 40
P-Site Similarity: N.A. N.A. N.A. N.A. 66.6 46.6
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 62 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 16 0 0 8 0 0 0 0 0 % D
% Glu: 0 8 0 0 0 0 0 0 0 0 0 0 0 0 0 % E
% Phe: 0 77 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 0 0 100 0 0 0 0 0 0 0 0 100 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 100 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 0 0 8 0 0 8 0 % I
% Lys: 0 0 0 93 16 0 0 8 0 0 0 0 0 8 0 % K
% Leu: 0 0 0 0 0 0 0 8 0 0 0 0 0 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 8 0 0 8 0 0 0 0 0 0 0 % N
% Pro: 0 0 93 0 0 0 0 0 0 0 0 0 0 0 0 % P
% Gln: 0 0 0 0 0 0 85 0 0 0 0 0 0 0 0 % Q
% Arg: 8 0 0 8 62 0 0 0 0 0 0 0 0 0 0 % R
% Ser: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % S
% Thr: 93 0 8 0 16 0 0 77 0 16 0 0 0 77 0 % T
% Val: 0 0 0 0 0 0 0 0 39 77 93 0 0 8 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 16 0 0 0 0 0 0 0 0 0 0 100 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _