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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: TRA2B All Species: 20
Human Site: S280 Identified Species: 44
UniProt: P62995 Number Species: 10
    Phosphosite Substitution
    Charge Score: -0.2
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P62995 NP_004584.1 288 33666 S280 G Y R S R S R S R S Y S P R R
Chimpanzee Pan troglodytes
Rhesus Macaque Macaca mulatta XP_001094519 268 31631 R261 Y R S R S R S R S Y S P R R Y
Dog Lupus familis XP_535833 471 53330 S463 G Y R S R S R S R S Y S P R R
Cat Felis silvestris
Mouse Mus musculus Q6PFR5 281 32298 R274 Y R S R S R S R S Y S P R R Y
Rat Rattus norvegicus P62997 288 33647 S280 G Y R S R S R S R S Y S P R R
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001514404 362 41750 S278 G Y R S R S R S R S Y S P R E
Chicken Gallus gallus
Frog Xenopus laevis Q9DED4 166 17837 Y159 G G S Y R D S Y D S Y A T H E
Zebra Danio Brachydanio rerio
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P19018 264 31013 S254 R S Y S R S R S P Q L R R T S
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans Q09511 196 22569 S189 R S A S R S P S R S R S N S R
Sea Urchin Strong. purpuratus XP_796831 284 33372 H271 H H S S R R H H Y Y P R E P R
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana O22315 303 33711 S277 R S R S P L P S V Q K E G S K
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 N.A. 93 61.1 N.A. 64.5 100 N.A. 77 N.A. 25.6 N.A. N.A. 38.8 N.A. 23.9 49.3
Protein Similarity: 100 N.A. 93 61.1 N.A. 72.5 100 N.A. 77.3 N.A. 32.2 N.A. N.A. 51.7 N.A. 34.3 59.7
P-Site Identity: 100 N.A. 6.6 100 N.A. 6.6 100 N.A. 93.3 N.A. 26.6 N.A. N.A. 33.3 N.A. 53.3 20
P-Site Similarity: 100 N.A. 6.6 100 N.A. 6.6 100 N.A. 93.3 N.A. 33.3 N.A. N.A. 33.3 N.A. 53.3 26.6
Percent
Protein Identity: N.A. N.A. N.A. 20.7 N.A. N.A.
Protein Similarity: N.A. N.A. N.A. 32.6 N.A. N.A.
P-Site Identity: N.A. N.A. N.A. 20 N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. 26.6 N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 10 0 0 0 0 0 0 0 0 10 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 10 0 0 10 0 0 0 0 0 0 % D
% Glu: 0 0 0 0 0 0 0 0 0 0 0 10 10 0 19 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 46 10 0 0 0 0 0 0 0 0 0 0 10 0 0 % G
% His: 10 10 0 0 0 0 10 10 0 0 0 0 0 10 0 % H
% Ile: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % I
% Lys: 0 0 0 0 0 0 0 0 0 0 10 0 0 0 10 % K
% Leu: 0 0 0 0 0 10 0 0 0 0 10 0 0 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 0 0 10 0 0 % N
% Pro: 0 0 0 0 10 0 19 0 10 0 10 19 37 10 0 % P
% Gln: 0 0 0 0 0 0 0 0 0 19 0 0 0 0 0 % Q
% Arg: 28 19 46 19 73 28 46 19 46 0 10 19 28 55 46 % R
% Ser: 0 28 37 73 19 55 28 64 19 55 19 46 0 19 10 % S
% Thr: 0 0 0 0 0 0 0 0 0 0 0 0 10 10 0 % T
% Val: 0 0 0 0 0 0 0 0 10 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 19 37 10 10 0 0 0 10 10 28 46 0 0 0 19 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _