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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
VAMP2
All Species:
30.3
Human Site:
S28
Identified Species:
55.56
UniProt:
P63027
Number Species:
12
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P63027
NP_055046
116
12663
S28
A
P
P
P
N
L
T
S
N
R
R
L
Q
Q
T
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
Q9N0Y0
116
12644
S28
A
P
P
P
N
L
T
S
N
R
R
L
Q
Q
T
Dog
Lupus familis
XP_536630
203
21289
S115
A
P
P
P
N
L
T
S
N
R
R
L
Q
Q
T
Cat
Felis silvestris
Mouse
Mus musculus
Q62442
118
12871
S30
G
P
P
P
N
M
T
S
N
R
R
L
Q
Q
T
Rat
Rattus norvegicus
P63045
116
12672
S28
A
P
P
P
N
L
T
S
N
R
R
L
Q
Q
T
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506423
126
13983
S33
N
P
P
T
N
V
T
S
N
R
R
L
Q
Q
T
Chicken
Gallus gallus
XP_422640
114
12506
S26
P
P
A
T
N
V
S
S
N
K
R
L
Q
Q
T
Frog
Xenopus laevis
P47193
114
12454
S26
Q
G
P
P
N
L
T
S
N
R
R
L
Q
Q
T
Zebra Danio
Brachydanio rerio
NP_956299
110
12110
N23
A
P
P
N
L
T
S
N
R
R
L
Q
Q
T
Q
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P18489
152
16693
A44
Q
I
R
N
N
N
A
A
Q
K
K
L
Q
Q
T
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
O02495
109
12007
R23
G
P
R
P
S
N
K
R
L
Q
Q
T
Q
A
Q
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9MAS5
220
24854
E127
Y
C
A
D
H
P
E
E
I
S
K
L
S
K
V
Baker's Yeast
Sacchar. cerevisiae
P33328
115
12939
S24
N
S
G
A
N
P
N
S
Q
N
K
T
A
A
L
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
100
56.6
N.A.
78.8
99.1
N.A.
75.4
80.1
87.9
87
N.A.
45.3
N.A.
63.7
N.A.
Protein Similarity:
100
N.A.
100
57.1
N.A.
86.4
99.1
N.A.
81.7
87
90.5
87.9
N.A.
55.9
N.A.
74.1
N.A.
P-Site Identity:
100
N.A.
100
100
N.A.
86.6
100
N.A.
80
60
86.6
33.3
N.A.
33.3
N.A.
20
N.A.
P-Site Similarity:
100
N.A.
100
100
N.A.
93.3
100
N.A.
86.6
80
86.6
46.6
N.A.
53.3
N.A.
40
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
24
35.3
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
36.8
60.3
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
6.6
13.3
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
26.6
20
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
39
0
16
8
0
0
8
8
0
0
0
0
8
16
0
% A
% Cys:
0
8
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
8
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
0
0
0
0
8
8
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
16
8
8
0
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
8
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
8
0
0
0
0
0
0
8
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
0
8
0
0
16
24
0
0
8
0
% K
% Leu:
0
0
0
0
8
39
0
0
8
0
8
77
0
0
8
% L
% Met:
0
0
0
0
0
8
0
0
0
0
0
0
0
0
0
% M
% Asn:
16
0
0
16
77
16
8
8
62
8
0
0
0
0
0
% N
% Pro:
8
70
62
54
0
16
0
0
0
0
0
0
0
0
0
% P
% Gln:
16
0
0
0
0
0
0
0
16
8
8
8
85
70
16
% Q
% Arg:
0
0
16
0
0
0
0
8
8
62
62
0
0
0
0
% R
% Ser:
0
8
0
0
8
0
16
70
0
8
0
0
8
0
0
% S
% Thr:
0
0
0
16
0
8
54
0
0
0
0
16
0
8
70
% T
% Val:
0
0
0
0
0
16
0
0
0
0
0
0
0
0
8
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
8
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _