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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: VAMP2 All Species: 43.33
Human Site: S75 Identified Species: 79.44
UniProt: P63027 Number Species: 12
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P63027 NP_055046 116 12663 S75 D A L Q A G A S Q F E T S A A
Chimpanzee Pan troglodytes
Rhesus Macaque Macaca mulatta Q9N0Y0 116 12644 S75 D A L Q A G A S Q F E T S A A
Dog Lupus familis XP_536630 203 21289 S162 D A L Q A G A S Q F E T S A A
Cat Felis silvestris
Mouse Mus musculus Q62442 118 12871 S77 D A L Q A G A S Q F E S S A A
Rat Rattus norvegicus P63045 116 12672 S75 D A L Q A G A S Q F E T S A A
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001506423 126 13983 S80 D A L Q A G A S Q F E T S A A
Chicken Gallus gallus XP_422640 114 12506 S73 D A L Q A G A S Q F E T S A A
Frog Xenopus laevis P47193 114 12454 S73 D A L Q A G A S Q F E T S A A
Zebra Danio Brachydanio rerio NP_956299 110 12110 S69 D A L Q A G A S Q F E T S A A
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P18489 152 16693 S91 D Q L E Q G A S Q F E Q Q A G
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans O02495 109 12007 S67 D A L Q E G A S Q F E K S A A
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9MAS5 220 24854 Q174 E N L R S Q A Q D F R T Q G T
Baker's Yeast Sacchar. cerevisiae P33328 115 12939 Q71 D N L A I S A Q G F K R G A N
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 N.A. 100 56.6 N.A. 78.8 99.1 N.A. 75.4 80.1 87.9 87 N.A. 45.3 N.A. 63.7 N.A.
Protein Similarity: 100 N.A. 100 57.1 N.A. 86.4 99.1 N.A. 81.7 87 90.5 87.9 N.A. 55.9 N.A. 74.1 N.A.
P-Site Identity: 100 N.A. 100 100 N.A. 93.3 100 N.A. 100 100 100 100 N.A. 60 N.A. 86.6 N.A.
P-Site Similarity: 100 N.A. 100 100 N.A. 100 100 N.A. 100 100 100 100 N.A. 66.6 N.A. 86.6 N.A.
Percent
Protein Identity: N.A. N.A. N.A. 24 35.3 N.A.
Protein Similarity: N.A. N.A. N.A. 36.8 60.3 N.A.
P-Site Identity: N.A. N.A. N.A. 26.6 33.3 N.A.
P-Site Similarity: N.A. N.A. N.A. 46.6 40 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 77 0 8 70 0 100 0 0 0 0 0 0 93 77 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 93 0 0 0 0 0 0 0 8 0 0 0 0 0 0 % D
% Glu: 8 0 0 8 8 0 0 0 0 0 85 0 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 100 0 0 0 0 0 % F
% Gly: 0 0 0 0 0 85 0 0 8 0 0 0 8 8 8 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 8 0 0 0 0 0 0 0 0 0 0 % I
% Lys: 0 0 0 0 0 0 0 0 0 0 8 8 0 0 0 % K
% Leu: 0 0 100 0 0 0 0 0 0 0 0 0 0 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 16 0 0 0 0 0 0 0 0 0 0 0 0 8 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % P
% Gln: 0 8 0 77 8 8 0 16 85 0 0 8 16 0 0 % Q
% Arg: 0 0 0 8 0 0 0 0 0 0 8 8 0 0 0 % R
% Ser: 0 0 0 0 8 8 0 85 0 0 0 8 77 0 0 % S
% Thr: 0 0 0 0 0 0 0 0 0 0 0 70 0 0 8 % T
% Val: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _