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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
VAMP2
All Species:
36.06
Human Site:
T35
Identified Species:
66.11
UniProt:
P63027
Number Species:
12
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P63027
NP_055046
116
12663
T35
S
N
R
R
L
Q
Q
T
Q
A
Q
V
D
E
V
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
Q9N0Y0
116
12644
T35
S
N
R
R
L
Q
Q
T
Q
A
Q
V
D
E
V
Dog
Lupus familis
XP_536630
203
21289
T122
S
N
R
R
L
Q
Q
T
Q
A
Q
V
D
E
V
Cat
Felis silvestris
Mouse
Mus musculus
Q62442
118
12871
T37
S
N
R
R
L
Q
Q
T
Q
A
Q
V
E
E
V
Rat
Rattus norvegicus
P63045
116
12672
T35
S
N
R
R
L
Q
Q
T
Q
A
Q
V
D
E
V
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506423
126
13983
T40
S
N
R
R
L
Q
Q
T
Q
A
Q
V
D
E
V
Chicken
Gallus gallus
XP_422640
114
12506
T33
S
N
K
R
L
Q
Q
T
Q
A
Q
V
D
E
V
Frog
Xenopus laevis
P47193
114
12454
T33
S
N
R
R
L
Q
Q
T
Q
A
Q
V
D
E
V
Zebra Danio
Brachydanio rerio
NP_956299
110
12110
Q30
N
R
R
L
Q
Q
T
Q
A
Q
V
D
E
V
V
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P18489
152
16693
T51
A
Q
K
K
L
Q
Q
T
Q
A
K
V
D
E
V
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
O02495
109
12007
Q30
R
L
Q
Q
T
Q
A
Q
V
D
E
V
V
G
I
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9MAS5
220
24854
V134
E
I
S
K
L
S
K
V
K
A
Q
V
T
E
V
Baker's Yeast
Sacchar. cerevisiae
P33328
115
12939
L31
S
Q
N
K
T
A
A
L
R
Q
E
I
D
D
T
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
100
56.6
N.A.
78.8
99.1
N.A.
75.4
80.1
87.9
87
N.A.
45.3
N.A.
63.7
N.A.
Protein Similarity:
100
N.A.
100
57.1
N.A.
86.4
99.1
N.A.
81.7
87
90.5
87.9
N.A.
55.9
N.A.
74.1
N.A.
P-Site Identity:
100
N.A.
100
100
N.A.
93.3
100
N.A.
100
93.3
100
20
N.A.
66.6
N.A.
13.3
N.A.
P-Site Similarity:
100
N.A.
100
100
N.A.
100
100
N.A.
100
100
100
33.3
N.A.
93.3
N.A.
40
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
24
35.3
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
36.8
60.3
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
40
13.3
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
60
46.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
0
0
0
0
8
16
0
8
77
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
8
0
8
70
8
0
% D
% Glu:
8
0
0
0
0
0
0
0
0
0
16
0
16
77
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
0
0
8
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
8
0
0
0
0
0
0
0
0
0
8
0
0
8
% I
% Lys:
0
0
16
24
0
0
8
0
8
0
8
0
0
0
0
% K
% Leu:
0
8
0
8
77
0
0
8
0
0
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
8
62
8
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
16
8
8
8
85
70
16
70
16
70
0
0
0
0
% Q
% Arg:
8
8
62
62
0
0
0
0
8
0
0
0
0
0
0
% R
% Ser:
70
0
8
0
0
8
0
0
0
0
0
0
0
0
0
% S
% Thr:
0
0
0
0
16
0
8
70
0
0
0
0
8
0
8
% T
% Val:
0
0
0
0
0
0
0
8
8
0
8
85
8
8
85
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _