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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: GNAS All Species: 45.15
Human Site: T350 Identified Species: 90.3
UniProt: P63092 Number Species: 11
    Phosphosite Substitution
    Charge Score: -0.09
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P63092 NP_000507.1 394 45665 T350 D E F L R I S T A S G D G R H
Chimpanzee Pan troglodytes XP_525370 1056 112593 T1012 D E F L R I S T A S G D G R H
Rhesus Macaque Macaca mulatta XP_001083581 1043 111280 T999 D E F L R I S T A S G D G R H
Dog Lupus familis XP_860224 381 44265 T337 D L F L R I S T A T G D G K H
Cat Felis silvestris
Mouse Mus musculus Q6R0H7 1133 121487 T1089 D E F L R I S T A S G D G R H
Rat Rattus norvegicus P63095 394 45645 T350 D E F L R I S T A S G D G R H
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001511277 510 57572 T466 D E F L R I S T A S G D G R H
Chicken Gallus gallus XP_001231542 398 46270 T354 D E F L R I S T A S G D G R H
Frog Xenopus laevis P24799 379 44528 T335 D E F L R I S T A S G D G R H
Zebra Danio Brachydanio rerio XP_685500 379 44458 T335 D E F L R I S T A S G D G R H
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P20354 385 44980 T341 D E F L R I S T A S G D G K H
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans P51875 354 40433 K313 A Q F E A K N K S A N K E I Y
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 36.6 37 77.9 N.A. 34 99.7 N.A. 61.7 90.4 88.8 86.8 N.A. 70.8 N.A. 41.1 N.A.
Protein Similarity: 100 37.2 37.6 87.8 N.A. 34.6 100 N.A. 67 94.4 91.6 92.1 N.A. 81.9 N.A. 57.1 N.A.
P-Site Identity: 100 100 100 80 N.A. 100 100 N.A. 100 100 100 100 N.A. 93.3 N.A. 6.6 N.A.
P-Site Similarity: 100 100 100 93.3 N.A. 100 100 N.A. 100 100 100 100 N.A. 100 N.A. 40 N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 9 0 0 0 9 0 0 0 92 9 0 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 92 0 0 0 0 0 0 0 0 0 0 92 0 0 0 % D
% Glu: 0 84 0 9 0 0 0 0 0 0 0 0 9 0 0 % E
% Phe: 0 0 100 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 0 0 0 0 0 0 0 92 0 92 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 92 % H
% Ile: 0 0 0 0 0 92 0 0 0 0 0 0 0 9 0 % I
% Lys: 0 0 0 0 0 9 0 9 0 0 0 9 0 17 0 % K
% Leu: 0 9 0 92 0 0 0 0 0 0 0 0 0 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 9 0 0 0 9 0 0 0 0 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % P
% Gln: 0 9 0 0 0 0 0 0 0 0 0 0 0 0 0 % Q
% Arg: 0 0 0 0 92 0 0 0 0 0 0 0 0 75 0 % R
% Ser: 0 0 0 0 0 0 92 0 9 84 0 0 0 0 0 % S
% Thr: 0 0 0 0 0 0 0 92 0 9 0 0 0 0 0 % T
% Val: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _