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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
GNAS
All Species:
40.3
Human Site:
Y318
Identified Species:
80.61
UniProt:
P63092
Number Species:
11
Phosphosite Substitution
Charge Score:
-0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P63092
NP_000507.1
394
45665
Y318
Y
F
P
E
F
A
R
Y
T
T
P
E
D
A
T
Chimpanzee
Pan troglodytes
XP_525370
1056
112593
Y980
Y
F
P
E
F
A
R
Y
T
T
P
E
D
A
T
Rhesus Macaque
Macaca mulatta
XP_001083581
1043
111280
Y967
Y
F
P
E
F
A
R
Y
T
T
P
E
D
A
T
Dog
Lupus familis
XP_860224
381
44265
Y305
Y
F
P
E
Y
A
N
Y
T
V
P
E
D
A
T
Cat
Felis silvestris
Mouse
Mus musculus
Q6R0H7
1133
121487
Y1057
Y
F
P
E
F
A
R
Y
T
T
P
E
D
A
T
Rat
Rattus norvegicus
P63095
394
45645
Y318
Y
F
P
E
F
A
R
Y
T
T
P
E
D
A
T
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001511277
510
57572
Y434
Y
F
P
E
F
A
R
Y
T
T
P
D
D
A
T
Chicken
Gallus gallus
XP_001231542
398
46270
Y322
Y
F
P
E
F
A
R
Y
T
T
P
D
D
A
T
Frog
Xenopus laevis
P24799
379
44528
Y303
Y
F
P
E
F
A
R
Y
T
T
P
D
D
A
T
Zebra Danio
Brachydanio rerio
XP_685500
379
44458
Y303
Y
F
P
E
F
A
R
Y
T
T
P
D
D
A
T
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P20354
385
44980
P309
E
F
N
K
Y
Q
T
P
I
D
T
G
D
A
I
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
P51875
354
40433
K281
L
F
E
E
K
I
K
K
S
P
L
T
I
C
F
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
36.6
37
77.9
N.A.
34
99.7
N.A.
61.7
90.4
88.8
86.8
N.A.
70.8
N.A.
41.1
N.A.
Protein Similarity:
100
37.2
37.6
87.8
N.A.
34.6
100
N.A.
67
94.4
91.6
92.1
N.A.
81.9
N.A.
57.1
N.A.
P-Site Identity:
100
100
100
80
N.A.
100
100
N.A.
93.3
93.3
93.3
93.3
N.A.
20
N.A.
13.3
N.A.
P-Site Similarity:
100
100
100
86.6
N.A.
100
100
N.A.
100
100
100
100
N.A.
33.3
N.A.
26.6
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
84
0
0
0
0
0
0
0
92
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
9
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
9
0
34
92
0
0
% D
% Glu:
9
0
9
92
0
0
0
0
0
0
0
50
0
0
0
% E
% Phe:
0
100
0
0
75
0
0
0
0
0
0
0
0
0
9
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
9
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
9
0
0
9
0
0
0
9
0
9
% I
% Lys:
0
0
0
9
9
0
9
9
0
0
0
0
0
0
0
% K
% Leu:
9
0
0
0
0
0
0
0
0
0
9
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
9
0
0
0
9
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
84
0
0
0
0
9
0
9
84
0
0
0
0
% P
% Gln:
0
0
0
0
0
9
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
75
0
0
0
0
0
0
0
0
% R
% Ser:
0
0
0
0
0
0
0
0
9
0
0
0
0
0
0
% S
% Thr:
0
0
0
0
0
0
9
0
84
75
9
9
0
0
84
% T
% Val:
0
0
0
0
0
0
0
0
0
9
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
84
0
0
0
17
0
0
84
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _