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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: GNAI1 All Species: 40
Human Site: Y74 Identified Species: 73.33
UniProt: P63096 Number Species: 12
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P63096 NP_002060.4 354 40361 Y74 K Q Y K A V V Y S N T I Q S I
Chimpanzee Pan troglodytes XP_527799 302 34756 G44 G R L K I D F G D S A R A D D
Rhesus Macaque Macaca mulatta XP_001108656 360 41440 H74 K I F G L L F H M K S L I F Q
Dog Lupus familis XP_535402 401 45799 Y121 K Q Y K A V V Y S N T I Q S I
Cat Felis silvestris
Mouse Mus musculus Q9DC51 354 40520 Y74 K Q Y K V V V Y S N T I Q S I
Rat Rattus norvegicus P10824 354 40327 Y74 K Q Y K A V V Y S N T I Q S I
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001507140 382 43916 Y102 K Q Y K A V V Y S N T I Q S I
Chicken Gallus gallus P50146 354 40360 Y74 K Q Y K A V V Y S N T I Q S I
Frog Xenopus laevis P27044 354 40383 Y74 K Q Y K A V V Y S N T I Q S I
Zebra Danio Brachydanio rerio NP_957265 354 40310 Y74 K Q Y K A V V Y S N T I Q S I
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P20353 355 40577 F75 E E Y R R V V F S N T V Q S L
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans P51875 354 40433 Y74 K Q Y K P V V Y S N T V Q S L
Sea Urchin Strong. purpuratus NP_001001475 354 40273 Y74 R Q Y K P V V Y S N T I Q S M
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 85.3 87.5 82.2 N.A. 93.7 99.7 N.A. 85.3 98 98 96.8 N.A. 77.7 N.A. 70.3 88.9
Protein Similarity: 100 85.3 91.6 85 N.A. 98.3 100 N.A. 86.3 99.1 98.8 98.5 N.A. 87.6 N.A. 84.4 93.7
P-Site Identity: 100 6.6 6.6 100 N.A. 93.3 100 N.A. 100 100 100 100 N.A. 53.3 N.A. 80 80
P-Site Similarity: 100 20 40 100 N.A. 93.3 100 N.A. 100 100 100 100 N.A. 93.3 N.A. 93.3 93.3
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 54 0 0 0 0 0 8 0 8 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 8 0 0 8 0 0 0 0 8 8 % D
% Glu: 8 8 0 0 0 0 0 0 0 0 0 0 0 0 0 % E
% Phe: 0 0 8 0 0 0 16 8 0 0 0 0 0 8 0 % F
% Gly: 8 0 0 8 0 0 0 8 0 0 0 0 0 0 0 % G
% His: 0 0 0 0 0 0 0 8 0 0 0 0 0 0 0 % H
% Ile: 0 8 0 0 8 0 0 0 0 0 0 70 8 0 62 % I
% Lys: 77 0 0 85 0 0 0 0 0 8 0 0 0 0 0 % K
% Leu: 0 0 8 0 8 8 0 0 0 0 0 8 0 0 16 % L
% Met: 0 0 0 0 0 0 0 0 8 0 0 0 0 0 8 % M
% Asn: 0 0 0 0 0 0 0 0 0 85 0 0 0 0 0 % N
% Pro: 0 0 0 0 16 0 0 0 0 0 0 0 0 0 0 % P
% Gln: 0 77 0 0 0 0 0 0 0 0 0 0 85 0 8 % Q
% Arg: 8 8 0 8 8 0 0 0 0 0 0 8 0 0 0 % R
% Ser: 0 0 0 0 0 0 0 0 85 8 8 0 0 85 0 % S
% Thr: 0 0 0 0 0 0 0 0 0 0 85 0 0 0 0 % T
% Val: 0 0 0 0 8 85 85 0 0 0 0 16 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 85 0 0 0 0 77 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _