KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PPP3R1
All Species:
57.88
Human Site:
S149
Identified Species:
84.89
UniProt:
P63098
Number Species:
15
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P63098
NP_000936.1
170
19300
S149
K
D
G
D
G
R
I
S
F
E
E
F
C
A
V
Chimpanzee
Pan troglodytes
XP_001136329
173
19833
S152
K
D
G
D
G
K
I
S
F
E
E
F
S
A
V
Rhesus Macaque
Macaca mulatta
XP_001110425
173
19841
S152
K
D
G
D
G
K
I
S
F
E
E
F
S
A
V
Dog
Lupus familis
XP_855383
176
20041
S155
K
D
G
D
G
R
I
S
F
E
E
F
C
A
V
Cat
Felis silvestris
Mouse
Mus musculus
Q63811
179
20641
S149
K
D
G
D
G
R
I
S
F
E
E
F
S
D
V
Rat
Rattus norvegicus
P63100
170
19281
S149
K
D
G
D
G
R
I
S
F
E
E
F
C
A
V
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001514232
313
34681
S292
K
D
G
D
G
R
I
S
F
E
E
F
C
A
V
Chicken
Gallus gallus
Q5ZM44
195
22429
S172
Q
D
G
D
C
A
I
S
F
A
E
F
V
K
V
Frog
Xenopus laevis
Q6DCM9
193
22267
S165
T
N
N
D
G
K
L
S
L
E
E
F
I
K
G
Zebra Danio
Brachydanio rerio
A9JTH1
193
22206
S165
T
N
R
D
G
K
L
S
L
E
E
F
I
K
G
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q24214
170
19248
S149
K
D
E
D
G
K
I
S
F
D
E
F
C
S
V
Honey Bee
Apis mellifera
XP_623751
162
18522
S141
K
D
E
D
G
K
I
S
F
E
E
F
C
S
V
Nematode Worm
Caenorhab. elegans
NP_505885
171
19654
S149
K
D
G
D
G
K
I
S
F
Q
E
F
C
D
V
Sea Urchin
Strong. purpuratus
XP_795492
170
19291
S149
L
D
G
D
G
K
I
S
Y
D
E
F
C
T
V
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P25296
175
19620
S152
S
D
G
D
G
R
L
S
F
E
E
F
K
N
A
Red Bread Mold
Neurospora crassa
P87072
174
19751
S152
L
D
K
D
G
K
I
S
F
E
E
F
T
K
M
Conservation
Percent
Protein Identity:
100
82.6
80.9
90.9
N.A.
76.5
100
N.A.
52.4
40.5
29.5
29
N.A.
87.6
84.1
78.3
84.1
Protein Similarity:
100
89.5
89.5
91.4
N.A.
84.9
100
N.A.
53.9
56.9
48.7
49.2
N.A.
93.5
90
91.2
93.5
P-Site Identity:
100
86.6
86.6
100
N.A.
86.6
100
N.A.
100
60
40
40
N.A.
73.3
80
80
66.6
P-Site Similarity:
100
93.3
93.3
100
N.A.
86.6
100
N.A.
100
66.6
60
60
N.A.
93.3
93.3
93.3
86.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
55.4
61.4
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
74.8
76.4
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
66.6
60
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
73.3
73.3
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
7
0
0
0
7
0
0
0
38
7
% A
% Cys:
0
0
0
0
7
0
0
0
0
0
0
0
50
0
0
% C
% Asp:
0
88
0
100
0
0
0
0
0
13
0
0
0
13
0
% D
% Glu:
0
0
13
0
0
0
0
0
0
75
100
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
82
0
0
100
0
0
0
% F
% Gly:
0
0
69
0
94
0
0
0
0
0
0
0
0
0
13
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
82
0
0
0
0
0
13
0
0
% I
% Lys:
63
0
7
0
0
57
0
0
0
0
0
0
7
25
0
% K
% Leu:
13
0
0
0
0
0
19
0
13
0
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
7
% M
% Asn:
0
13
7
0
0
0
0
0
0
0
0
0
0
7
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
7
0
0
0
0
0
0
0
0
7
0
0
0
0
0
% Q
% Arg:
0
0
7
0
0
38
0
0
0
0
0
0
0
0
0
% R
% Ser:
7
0
0
0
0
0
0
100
0
0
0
0
19
13
0
% S
% Thr:
13
0
0
0
0
0
0
0
0
0
0
0
7
7
0
% T
% Val:
0
0
0
0
0
0
0
0
0
0
0
0
7
0
75
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
7
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _