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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PPP3R1
All Species:
51.21
Human Site:
S35
Identified Species:
75.11
UniProt:
P63098
Number Species:
15
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P63098
NP_000936.1
170
19300
S35
K
K
L
D
L
D
N
S
G
S
L
S
V
E
E
Chimpanzee
Pan troglodytes
XP_001136329
173
19833
S38
K
K
L
D
L
D
K
S
G
S
L
S
V
E
E
Rhesus Macaque
Macaca mulatta
XP_001110425
173
19841
S38
R
K
L
D
L
D
K
S
G
S
L
S
V
E
E
Dog
Lupus familis
XP_855383
176
20041
S41
K
K
L
D
L
D
N
S
G
S
L
S
V
E
E
Cat
Felis silvestris
Mouse
Mus musculus
Q63811
179
20641
S35
R
K
L
D
L
D
K
S
G
S
L
S
I
E
E
Rat
Rattus norvegicus
P63100
170
19281
S35
K
K
L
D
L
D
N
S
G
S
L
S
V
E
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001514232
313
34681
S178
K
K
L
D
L
D
N
S
G
S
L
S
V
E
E
Chicken
Gallus gallus
Q5ZM44
195
22429
N43
T
S
L
D
K
G
E
N
G
T
L
S
R
E
D
Frog
Xenopus laevis
Q6DCM9
193
22267
T40
G
F
L
K
D
C
P
T
G
H
L
T
V
E
E
Zebra Danio
Brachydanio rerio
A9JTH1
193
22206
S40
G
F
L
R
D
C
P
S
G
N
L
S
M
E
E
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q24214
170
19248
S35
R
K
L
D
L
D
N
S
G
A
L
S
V
D
E
Honey Bee
Apis mellifera
XP_623751
162
18522
A29
L
D
L
D
N
S
G
A
L
S
I
D
E
F
M
Nematode Worm
Caenorhab. elegans
NP_505885
171
19654
S35
K
K
L
D
V
D
G
S
G
S
L
S
V
E
E
Sea Urchin
Strong. purpuratus
XP_795492
170
19291
S35
K
K
L
D
L
D
N
S
G
S
L
S
V
D
E
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P25296
175
19620
S38
M
K
L
D
R
D
S
S
G
S
I
D
K
N
E
Red Bread Mold
Neurospora crassa
P87072
174
19751
S38
M
K
L
D
K
D
N
S
G
T
I
E
R
E
E
Conservation
Percent
Protein Identity:
100
82.6
80.9
90.9
N.A.
76.5
100
N.A.
52.4
40.5
29.5
29
N.A.
87.6
84.1
78.3
84.1
Protein Similarity:
100
89.5
89.5
91.4
N.A.
84.9
100
N.A.
53.9
56.9
48.7
49.2
N.A.
93.5
90
91.2
93.5
P-Site Identity:
100
93.3
86.6
100
N.A.
80
100
N.A.
100
40
40
46.6
N.A.
80
20
86.6
93.3
P-Site Similarity:
100
93.3
93.3
100
N.A.
93.3
100
N.A.
100
60
53.3
60
N.A.
100
33.3
93.3
100
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
55.4
61.4
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
74.8
76.4
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
53.3
60
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
66.6
73.3
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
7
0
7
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
13
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
7
0
88
13
75
0
0
0
0
0
13
0
13
7
% D
% Glu:
0
0
0
0
0
0
7
0
0
0
0
7
7
75
88
% E
% Phe:
0
13
0
0
0
0
0
0
0
0
0
0
0
7
0
% F
% Gly:
13
0
0
0
0
7
13
0
94
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
7
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
19
0
7
0
0
% I
% Lys:
44
75
0
7
13
0
19
0
0
0
0
0
7
0
0
% K
% Leu:
7
0
100
0
57
0
0
0
7
0
82
0
0
0
0
% L
% Met:
13
0
0
0
0
0
0
0
0
0
0
0
7
0
7
% M
% Asn:
0
0
0
0
7
0
44
7
0
7
0
0
0
7
0
% N
% Pro:
0
0
0
0
0
0
13
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
19
0
0
7
7
0
0
0
0
0
0
0
13
0
0
% R
% Ser:
0
7
0
0
0
7
7
82
0
69
0
75
0
0
0
% S
% Thr:
7
0
0
0
0
0
0
7
0
13
0
7
0
0
0
% T
% Val:
0
0
0
0
7
0
0
0
0
0
0
0
63
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _