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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PPP3R1
All Species:
38.48
Human Site:
Y106
Identified Species:
56.44
UniProt:
P63098
Number Species:
15
Phosphosite Substitution
Charge Score:
-0.07
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P63098
NP_000936.1
170
19300
Y106
Y
D
M
D
K
D
G
Y
I
S
N
G
E
L
F
Chimpanzee
Pan troglodytes
XP_001136329
173
19833
Y109
Y
D
M
D
K
D
G
Y
I
S
N
G
E
L
F
Rhesus Macaque
Macaca mulatta
XP_001110425
173
19841
Y109
Y
D
M
D
K
D
G
Y
I
S
N
G
E
L
F
Dog
Lupus familis
XP_855383
176
20041
Y112
Y
D
M
D
K
D
G
Y
I
S
N
G
E
L
F
Cat
Felis silvestris
Mouse
Mus musculus
Q63811
179
20641
F106
Y
D
M
D
N
D
G
F
I
S
N
G
E
L
F
Rat
Rattus norvegicus
P63100
170
19281
Y106
Y
D
M
D
K
D
G
Y
I
S
N
G
E
L
F
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001514232
313
34681
Y249
Y
D
M
D
K
D
G
Y
I
S
N
G
E
L
F
Chicken
Gallus gallus
Q5ZM44
195
22429
K129
Y
D
L
D
K
D
D
K
I
S
R
D
E
L
L
Frog
Xenopus laevis
Q6DCM9
193
22267
Y115
Y
D
L
D
G
N
G
Y
I
S
R
G
E
M
L
Zebra Danio
Brachydanio rerio
A9JTH1
193
22206
Y115
Y
D
L
D
G
N
G
Y
I
S
K
S
E
M
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q24214
170
19248
Y106
Y
D
M
D
N
D
G
Y
I
S
N
G
E
L
F
Honey Bee
Apis mellifera
XP_623751
162
18522
F98
Y
D
M
D
N
D
G
F
I
S
N
G
E
L
F
Nematode Worm
Caenorhab. elegans
NP_505885
171
19654
F106
Y
D
M
D
R
D
G
F
I
S
N
G
E
L
F
Sea Urchin
Strong. purpuratus
XP_795492
170
19291
F106
Y
D
M
D
R
D
G
F
I
S
N
G
E
L
F
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P25296
175
19620
F109
Y
D
I
D
K
D
G
F
I
S
N
G
E
L
F
Red Bread Mold
Neurospora crassa
P87072
174
19751
Y109
Y
D
I
D
R
D
G
Y
I
S
N
G
E
L
F
Conservation
Percent
Protein Identity:
100
82.6
80.9
90.9
N.A.
76.5
100
N.A.
52.4
40.5
29.5
29
N.A.
87.6
84.1
78.3
84.1
Protein Similarity:
100
89.5
89.5
91.4
N.A.
84.9
100
N.A.
53.9
56.9
48.7
49.2
N.A.
93.5
90
91.2
93.5
P-Site Identity:
100
100
100
100
N.A.
86.6
100
N.A.
100
60
60
53.3
N.A.
93.3
86.6
86.6
86.6
P-Site Similarity:
100
100
100
100
N.A.
93.3
100
N.A.
100
66.6
80
73.3
N.A.
93.3
93.3
100
100
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
55.4
61.4
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
74.8
76.4
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
86.6
86.6
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
100
100
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
100
0
100
0
88
7
0
0
0
0
7
0
0
0
% D
% Glu:
0
0
0
0
0
0
0
0
0
0
0
0
100
0
0
% E
% Phe:
0
0
0
0
0
0
0
32
0
0
0
0
0
0
82
% F
% Gly:
0
0
0
0
13
0
94
0
0
0
0
88
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
13
0
0
0
0
0
100
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
50
0
0
7
0
0
7
0
0
0
0
% K
% Leu:
0
0
19
0
0
0
0
0
0
0
0
0
0
88
19
% L
% Met:
0
0
69
0
0
0
0
0
0
0
0
0
0
13
0
% M
% Asn:
0
0
0
0
19
13
0
0
0
0
82
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
19
0
0
0
0
0
13
0
0
0
0
% R
% Ser:
0
0
0
0
0
0
0
0
0
100
0
7
0
0
0
% S
% Thr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% T
% Val:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
100
0
0
0
0
0
0
63
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _