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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
YWHAZ
All Species:
57.27
Human Site:
S230
Identified Species:
90
UniProt:
P63104
Number Species:
14
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P63104
NP_001129171.1
245
27745
S230
D
N
L
T
L
W
T
S
D
T
Q
G
D
E
A
Chimpanzee
Pan troglodytes
XP_528202
382
42115
S367
D
N
L
T
L
W
T
S
D
T
Q
G
D
E
A
Rhesus Macaque
Macaca mulatta
XP_001098275
578
62565
S563
D
N
L
T
L
W
T
S
D
T
Q
G
D
E
A
Dog
Lupus familis
XP_850323
289
32637
S274
D
N
L
T
L
W
T
S
D
T
Q
G
D
E
A
Cat
Felis silvestris
Mouse
Mus musculus
Q9CQV8
246
28068
S232
D
N
L
T
L
W
T
S
E
N
Q
G
D
E
G
Rat
Rattus norvegicus
P63102
245
27753
S230
D
N
L
T
L
W
T
S
D
T
Q
G
D
E
A
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001509087
339
37959
S230
D
N
L
T
L
W
T
S
D
T
Q
G
E
G
D
Chicken
Gallus gallus
Q5ZKC9
245
27757
S230
D
N
L
T
L
W
T
S
D
T
Q
G
D
E
A
Frog
Xenopus laevis
Q91896
245
27711
S230
D
N
L
T
L
W
T
S
D
T
Q
G
D
E
A
Zebra Danio
Brachydanio rerio
Q5PRD0
244
27628
S230
D
N
L
T
L
W
T
S
E
N
Q
G
D
E
G
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P29310
248
28209
S233
D
N
L
T
L
W
T
S
D
T
Q
G
D
E
A
Honey Bee
Apis mellifera
XP_391841
247
28058
S232
D
N
L
T
L
W
T
S
D
T
Q
G
D
A
D
Nematode Worm
Caenorhab. elegans
Q20655
248
28049
S232
D
N
L
T
L
W
T
S
D
A
A
T
D
D
T
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q01525
259
29143
S236
D
N
L
T
L
W
T
S
D
M
Q
D
D
A
A
Baker's Yeast
Sacchar. cerevisiae
P34730
273
31043
S235
D
N
L
T
L
W
T
S
D
I
S
E
S
G
Q
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
64.1
42.3
84
N.A.
86.5
99.5
N.A.
71.9
99.1
89.3
86.9
N.A.
80.6
82.5
80.2
N.A.
Protein Similarity:
100
64.1
42.3
84
N.A.
93.5
99.5
N.A.
71.9
100
94.6
94.6
N.A.
89.1
91
89.9
N.A.
P-Site Identity:
100
100
100
100
N.A.
80
100
N.A.
80
100
100
80
N.A.
100
86.6
66.6
N.A.
P-Site Similarity:
100
100
100
100
N.A.
86.6
100
N.A.
86.6
100
100
86.6
N.A.
100
86.6
73.3
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
62.5
60.8
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
72.9
72.5
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
80
60
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
80
60
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
0
7
7
0
0
14
60
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
100
0
0
0
0
0
0
0
87
0
0
7
87
7
14
% D
% Glu:
0
0
0
0
0
0
0
0
14
0
0
7
7
67
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
80
0
14
14
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
7
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
0
0
100
0
100
0
0
0
0
0
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
7
0
0
0
0
0
% M
% Asn:
0
100
0
0
0
0
0
0
0
14
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
87
0
0
0
7
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
0
0
0
0
0
0
0
100
0
0
7
0
7
0
0
% S
% Thr:
0
0
0
100
0
0
100
0
0
67
0
7
0
0
7
% T
% Val:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
100
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _