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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: UBE2B All Species: 56.67
Human Site: S25 Identified Species: 83.11
UniProt: P63146 Number Species: 15
    Phosphosite Substitution
    Charge Score: 0.07
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P63146 NP_003328.1 152 17312 S25 E D P P V G V S G A P S E N N
Chimpanzee Pan troglodytes XP_001137388 247 26879 S120 E D P P A G V S G A P S E N N
Rhesus Macaque Macaca mulatta
Dog Lupus familis XP_549217 224 24534 S97 E D P P A G V S G A P S E N N
Cat Felis silvestris
Mouse Mus musculus Q9Z255 152 17297 S25 E D P P A G V S G A P S E N N
Rat Rattus norvegicus P63149 152 17294 S25 E D P P V G V S G A P S E N N
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001512900 156 17521 S29 E D P P V G V S G A P S E N N
Chicken Gallus gallus
Frog Xenopus laevis
Zebra Danio Brachydanio rerio NP_956013 152 17267 S25 E D P P A G V S G A P S E N N
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P25153 151 17134 S25 E D P P T G V S G A P T D N N
Honey Bee Apis mellifera XP_624240 151 17198 S25 E D P P T G V S G A P T D N N
Nematode Worm Caenorhab. elegans P52478 192 21494 S25 E D P P A G V S G A P T E D N
Sea Urchin Strong. purpuratus XP_795976 139 15590 E15 G V S G A P S E N N I M L W N
Poplar Tree Populus trichocarpa XP_002319717 152 17330 S25 Q D P P A G I S G A P Q D N N
Maize Zea mays NP_001146868 152 17321 S25 Q D P P A G I S G A P H D N N
Rice Oryza sativa
Thale Cress Arabidopsis thaliana P25865 152 17263 S25 Q D P P A G I S G A P Q D N N
Baker's Yeast Sacchar. cerevisiae P06104 172 19687 S25 E D A P P G V S A S P L P D N
Red Bread Mold Neurospora crassa P52493 151 17245 S25 T D P P A G V S A S P V P D N
Conservation
Percent
Protein Identity: 100 58.7 N.A. 64.7 N.A. 95.3 100 N.A. 90.3 N.A. N.A. 95.3 N.A. 85.5 86.1 66.6 80.2
Protein Similarity: 100 59.5 N.A. 65.6 N.A. 96.7 100 N.A. 91.6 N.A. N.A. 97.3 N.A. 92.1 92.1 75 85.5
P-Site Identity: 100 93.3 N.A. 93.3 N.A. 93.3 100 N.A. 100 N.A. N.A. 93.3 N.A. 80 80 80 6.6
P-Site Similarity: 100 93.3 N.A. 93.3 N.A. 93.3 100 N.A. 100 N.A. N.A. 93.3 N.A. 93.3 93.3 93.3 6.6
Percent
Protein Identity: 75 74.3 N.A. 75 61 67.7
Protein Similarity: 90.1 90.1 N.A. 90.1 76.1 83.5
P-Site Identity: 66.6 66.6 N.A. 66.6 53.3 53.3
P-Site Similarity: 86.6 86.6 N.A. 86.6 66.6 66.6
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 7 0 63 0 0 0 13 82 0 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 94 0 0 0 0 0 0 0 0 0 0 32 19 0 % D
% Glu: 69 0 0 0 0 0 0 7 0 0 0 0 50 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 7 0 0 7 0 94 0 0 82 0 0 0 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 7 0 0 0 % H
% Ile: 0 0 0 0 0 0 19 0 0 0 7 0 0 0 0 % I
% Lys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % K
% Leu: 0 0 0 0 0 0 0 0 0 0 0 7 7 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 7 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 7 7 0 0 0 75 100 % N
% Pro: 0 0 88 94 7 7 0 0 0 0 94 0 13 0 0 % P
% Gln: 19 0 0 0 0 0 0 0 0 0 0 13 0 0 0 % Q
% Arg: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % R
% Ser: 0 0 7 0 0 0 7 94 0 13 0 44 0 0 0 % S
% Thr: 7 0 0 0 13 0 0 0 0 0 0 19 0 0 0 % T
% Val: 0 7 0 0 19 0 75 0 0 0 0 7 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 7 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _