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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PPP2R2A
All Species:
39.09
Human Site:
S412
Identified Species:
78.18
UniProt:
P63151
Number Species:
11
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P63151
NP_002708.1
447
51692
S412
K
D
E
I
S
V
D
S
L
D
F
N
K
K
I
Chimpanzee
Pan troglodytes
XP_001162080
427
49781
S392
K
D
E
I
S
V
D
S
L
D
F
N
K
K
I
Rhesus Macaque
Macaca mulatta
XP_001091436
453
51968
S418
K
D
E
I
S
V
D
S
L
D
F
N
K
K
I
Dog
Lupus familis
XP_858358
449
51934
S414
K
D
E
I
S
V
D
S
L
D
F
N
K
K
I
Cat
Felis silvestris
Mouse
Mus musculus
Q6P1F6
447
51674
S412
K
D
E
I
S
V
D
S
L
D
F
N
K
K
I
Rat
Rattus norvegicus
P36876
447
51660
S412
K
D
E
I
S
V
D
S
L
D
F
N
K
K
I
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Q5ZIY5
451
51997
S416
K
D
E
I
N
V
D
S
L
D
F
N
K
K
I
Frog
Xenopus laevis
A1L3L9
468
54505
S433
K
D
E
I
S
V
D
S
L
D
F
S
K
K
I
Zebra Danio
Brachydanio rerio
NP_956070
448
51687
S413
K
D
E
I
S
V
D
S
L
D
F
N
K
K
I
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P36872
499
56948
C465
K
D
E
I
S
V
D
C
L
D
F
N
K
K
I
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q39247
501
56256
G457
M
T
R
V
V
R
R
G
S
E
S
P
G
T
E
Baker's Yeast
Sacchar. cerevisiae
Q00362
526
59644
S419
Q
N
K
D
S
S
S
S
G
N
S
H
K
R
R
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
94.6
88
99.5
N.A.
100
99.7
N.A.
N.A.
89.3
80.9
92.1
N.A.
70.7
N.A.
N.A.
N.A.
Protein Similarity:
100
95
94.2
99.5
N.A.
100
100
N.A.
N.A.
94.6
89.3
95.9
N.A.
79.3
N.A.
N.A.
N.A.
P-Site Identity:
100
100
100
100
N.A.
100
100
N.A.
N.A.
93.3
93.3
100
N.A.
93.3
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
N.A.
100
100
100
N.A.
93.3
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
50.7
48.1
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
66.6
63.1
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
0
20
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
13.3
60
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
9
0
0
0
0
0
0
0
% C
% Asp:
0
84
0
9
0
0
84
0
0
84
0
0
0
0
0
% D
% Glu:
0
0
84
0
0
0
0
0
0
9
0
0
0
0
9
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
84
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
9
9
0
0
0
9
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
9
0
0
0
% H
% Ile:
0
0
0
84
0
0
0
0
0
0
0
0
0
0
84
% I
% Lys:
84
0
9
0
0
0
0
0
0
0
0
0
92
84
0
% K
% Leu:
0
0
0
0
0
0
0
0
84
0
0
0
0
0
0
% L
% Met:
9
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
9
0
0
9
0
0
0
0
9
0
75
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
9
0
0
0
% P
% Gln:
9
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
9
0
0
9
9
0
0
0
0
0
0
9
9
% R
% Ser:
0
0
0
0
84
9
9
84
9
0
17
9
0
0
0
% S
% Thr:
0
9
0
0
0
0
0
0
0
0
0
0
0
9
0
% T
% Val:
0
0
0
9
9
84
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _