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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PPP2R2A
All Species:
19.7
Human Site:
Y189
Identified Species:
39.39
UniProt:
P63151
Number Species:
11
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P63151
NP_002708.1
447
51692
Y189
S
I
S
I
N
S
D
Y
E
T
Y
L
S
A
D
Chimpanzee
Pan troglodytes
XP_001162080
427
49781
Y169
S
I
S
I
N
S
D
Y
E
T
Y
L
S
A
D
Rhesus Macaque
Macaca mulatta
XP_001091436
453
51968
H195
S
I
S
V
N
S
D
H
E
T
Y
L
S
A
D
Dog
Lupus familis
XP_858358
449
51934
T191
S
I
N
S
D
Y
E
T
Y
L
S
A
D
D
L
Cat
Felis silvestris
Mouse
Mus musculus
Q6P1F6
447
51674
Y189
S
I
S
I
N
S
D
Y
E
T
Y
L
S
A
D
Rat
Rattus norvegicus
P36876
447
51660
Y189
S
I
S
I
N
S
D
Y
E
T
Y
L
S
A
D
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Q5ZIY5
451
51997
H193
S
I
S
V
N
S
D
H
E
T
Y
L
S
A
D
Frog
Xenopus laevis
A1L3L9
468
54505
Y210
S
I
S
V
N
S
D
Y
E
T
Y
M
S
A
D
Zebra Danio
Brachydanio rerio
NP_956070
448
51687
N190
S
I
S
V
N
S
D
N
E
T
Y
L
S
A
D
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P36872
499
56948
Q242
S
I
S
V
N
S
D
Q
E
T
F
L
S
A
D
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q39247
501
56256
G234
S
I
S
N
S
S
D
G
E
T
F
I
S
A
D
Baker's Yeast
Sacchar. cerevisiae
Q00362
526
59644
Q196
S
I
S
L
N
S
D
Q
E
T
F
L
S
A
D
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
94.6
88
99.5
N.A.
100
99.7
N.A.
N.A.
89.3
80.9
92.1
N.A.
70.7
N.A.
N.A.
N.A.
Protein Similarity:
100
95
94.2
99.5
N.A.
100
100
N.A.
N.A.
94.6
89.3
95.9
N.A.
79.3
N.A.
N.A.
N.A.
P-Site Identity:
100
100
86.6
13.3
N.A.
100
100
N.A.
N.A.
86.6
86.6
86.6
N.A.
80
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
100
33.3
N.A.
100
100
N.A.
N.A.
100
100
93.3
N.A.
93.3
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
50.7
48.1
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
66.6
63.1
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
66.6
80
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
86.6
93.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
0
0
0
9
0
92
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
9
0
92
0
0
0
0
0
9
9
92
% D
% Glu:
0
0
0
0
0
0
9
0
92
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
25
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
9
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
17
0
0
0
0
0
0
0
% H
% Ile:
0
100
0
34
0
0
0
0
0
0
0
9
0
0
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
0
0
0
9
0
0
0
0
0
9
0
75
0
0
9
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
9
0
0
0
% M
% Asn:
0
0
9
9
84
0
0
9
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
17
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
100
0
92
9
9
92
0
0
0
0
9
0
92
0
0
% S
% Thr:
0
0
0
0
0
0
0
9
0
92
0
0
0
0
0
% T
% Val:
0
0
0
42
0
0
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
9
0
42
9
0
67
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _