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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
GNB2L1
All Species:
32.73
Human Site:
S278
Identified Species:
48
UniProt:
P63244
Number Species:
15
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P63244
NP_006089.1
317
35077
S278
K
Q
E
V
I
S
T
S
S
K
A
E
P
P
Q
Chimpanzee
Pan troglodytes
Q5IS43
410
46712
T333
S
T
G
M
C
L
M
T
L
V
G
H
D
N
W
Rhesus Macaque
Macaca mulatta
XP_001105066
393
42789
S354
K
Q
E
V
I
S
T
S
S
K
A
E
P
P
Q
Dog
Lupus familis
XP_537934
316
34871
S277
K
Q
E
V
I
S
T
S
S
K
A
E
P
P
Q
Cat
Felis silvestris
Mouse
Mus musculus
Q8BHD1
476
53485
T402
L
M
P
E
C
S
S
T
T
V
K
K
R
P
E
Rat
Rattus norvegicus
P63245
317
35058
S278
K
Q
E
V
I
S
T
S
S
K
A
E
P
P
Q
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001511303
428
47737
S389
K
Q
E
V
I
S
T
S
S
K
A
E
P
P
Q
Chicken
Gallus gallus
Q9PTR5
410
46646
T333
S
T
G
M
C
L
M
T
L
V
G
H
D
N
W
Frog
Xenopus laevis
Q6DE72
410
46731
C356
G
G
K
F
I
L
S
C
A
D
D
K
T
I
R
Zebra Danio
Brachydanio rerio
O42248
317
35104
N278
R
Q
D
I
I
T
T
N
S
K
A
E
P
P
Q
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
O18640
318
35599
T279
R
P
E
V
V
S
P
T
S
K
A
D
Q
P
Q
Honey Bee
Apis mellifera
XP_392962
317
35737
T278
K
P
E
V
V
S
A
T
S
K
A
E
P
P
H
Nematode Worm
Caenorhab. elegans
Q21215
325
35812
S285
P
E
I
A
S
S
G
S
S
R
G
S
S
P
Q
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
O24456
327
35729
A280
K
V
D
L
K
A
E
A
E
K
A
D
N
S
G
Baker's Yeast
Sacchar. cerevisiae
P38011
319
34787
Y281
L
R
P
E
F
A
G
Y
S
K
A
A
E
P
H
Red Bread Mold
Neurospora crassa
Q01369
316
35112
G278
K
P
E
F
Q
N
I
G
K
K
S
R
E
P
E
Conservation
Percent
Protein Identity:
100
23.4
80.6
99.3
N.A.
23.9
100
N.A.
74
23.6
23.8
95.5
N.A.
76.4
79.5
71.3
N.A.
Protein Similarity:
100
39.5
80.6
99.3
N.A.
37.1
100
N.A.
74
39.5
39.2
99.6
N.A.
86.4
88.3
82.4
N.A.
P-Site Identity:
100
0
100
100
N.A.
13.3
100
N.A.
100
0
6.6
66.6
N.A.
53.3
66.6
33.3
N.A.
P-Site Similarity:
100
13.3
100
100
N.A.
46.6
100
N.A.
100
13.3
40
100
N.A.
80
80
46.6
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
65.4
52.9
70.6
Protein Similarity:
N.A.
N.A.
N.A.
77.3
70.2
83.6
P-Site Identity:
N.A.
N.A.
N.A.
20
26.6
26.6
P-Site Similarity:
N.A.
N.A.
N.A.
53.3
40
46.6
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
7
0
13
7
7
7
0
63
7
0
0
0
% A
% Cys:
0
0
0
0
19
0
0
7
0
0
0
0
0
0
0
% C
% Asp:
0
0
13
0
0
0
0
0
0
7
7
13
13
0
0
% D
% Glu:
0
7
50
13
0
0
7
0
7
0
0
44
13
0
13
% E
% Phe:
0
0
0
13
7
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
7
7
13
0
0
0
13
7
0
0
19
0
0
0
7
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
13
0
0
13
% H
% Ile:
0
0
7
7
44
0
7
0
0
0
0
0
0
7
0
% I
% Lys:
50
0
7
0
7
0
0
0
7
69
7
13
0
0
0
% K
% Leu:
13
0
0
7
0
19
0
0
13
0
0
0
0
0
0
% L
% Met:
0
7
0
13
0
0
13
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
7
0
7
0
0
0
0
7
13
0
% N
% Pro:
7
19
13
0
0
0
7
0
0
0
0
0
44
75
0
% P
% Gln:
0
38
0
0
7
0
0
0
0
0
0
0
7
0
50
% Q
% Arg:
13
7
0
0
0
0
0
0
0
7
0
7
7
0
7
% R
% Ser:
13
0
0
0
7
57
13
38
63
0
7
7
7
7
0
% S
% Thr:
0
13
0
0
0
7
38
32
7
0
0
0
7
0
0
% T
% Val:
0
7
0
44
13
0
0
0
0
19
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
13
% W
% Tyr:
0
0
0
0
0
0
0
7
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _