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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: GNB2L1 All Species: 43.94
Human Site: S292 Identified Species: 64.44
UniProt: P63244 Number Species: 15
    Phosphosite Substitution
    Charge Score: -0.13
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P63244 NP_006089.1 317 35077 S292 Q C T S L A W S A D G Q T L F
Chimpanzee Pan troglodytes Q5IS43 410 46712 H347 W V R G V L F H S G G K F I L
Rhesus Macaque Macaca mulatta XP_001105066 393 42789 S368 Q C T S L A W S A D G Q T L F
Dog Lupus familis XP_537934 316 34871 S291 Q C T S L A W S A D G Q T L F
Cat Felis silvestris
Mouse Mus musculus Q8BHD1 476 53485 S416 E D V S D V P S E S L R S V P
Rat Rattus norvegicus P63245 317 35058 S292 Q C T S L A W S A D G Q T L F
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001511303 428 47737 S403 Q C T S L A W S A D G Q T L F
Chicken Gallus gallus Q9PTR5 410 46646 H347 W V R G V L F H S G G K F I L
Frog Xenopus laevis Q6DE72 410 46731 K370 R I W D Y K N K R C M K T L N
Zebra Danio Brachydanio rerio O42248 317 35104 S292 Q C T S L A W S A D G Q T L F
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster O18640 318 35599 S293 Q C L S L A W S T D G Q T L F
Honey Bee Apis mellifera XP_392962 317 35737 S292 H C L S L A W S T D G Q T L F
Nematode Worm Caenorhab. elegans Q21215 325 35812 S299 Q C I S L A W S Q D G Q T L F
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana O24456 327 35729 K294 G P A A T K R K V I Y C T S L
Baker's Yeast Sacchar. cerevisiae P38011 319 34787 S295 H A V S L A W S A D G Q T L F
Red Bread Mold Neurospora crassa Q01369 316 35112 S292 E C V S L A W S A D G Q T L F
Conservation
Percent
Protein Identity: 100 23.4 80.6 99.3 N.A. 23.9 100 N.A. 74 23.6 23.8 95.5 N.A. 76.4 79.5 71.3 N.A.
Protein Similarity: 100 39.5 80.6 99.3 N.A. 37.1 100 N.A. 74 39.5 39.2 99.6 N.A. 86.4 88.3 82.4 N.A.
P-Site Identity: 100 6.6 100 100 N.A. 13.3 100 N.A. 100 6.6 13.3 100 N.A. 86.6 80 86.6 N.A.
P-Site Similarity: 100 40 100 100 N.A. 40 100 N.A. 100 40 26.6 100 N.A. 86.6 80 86.6 N.A.
Percent
Protein Identity: N.A. N.A. N.A. 65.4 52.9 70.6
Protein Similarity: N.A. N.A. N.A. 77.3 70.2 83.6
P-Site Identity: N.A. N.A. N.A. 6.6 80 86.6
P-Site Similarity: N.A. N.A. N.A. 13.3 80 93.3
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 7 7 7 0 69 0 0 50 0 0 0 0 0 0 % A
% Cys: 0 63 0 0 0 0 0 0 0 7 0 7 0 0 0 % C
% Asp: 0 7 0 7 7 0 0 0 0 69 0 0 0 0 0 % D
% Glu: 13 0 0 0 0 0 0 0 7 0 0 0 0 0 0 % E
% Phe: 0 0 0 0 0 0 13 0 0 0 0 0 13 0 69 % F
% Gly: 7 0 0 13 0 0 0 0 0 13 82 0 0 0 0 % G
% His: 13 0 0 0 0 0 0 13 0 0 0 0 0 0 0 % H
% Ile: 0 7 7 0 0 0 0 0 0 7 0 0 0 13 0 % I
% Lys: 0 0 0 0 0 13 0 13 0 0 0 19 0 0 0 % K
% Leu: 0 0 13 0 69 13 0 0 0 0 7 0 0 75 19 % L
% Met: 0 0 0 0 0 0 0 0 0 0 7 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 7 0 0 0 0 0 0 0 7 % N
% Pro: 0 7 0 0 0 0 7 0 0 0 0 0 0 0 7 % P
% Gln: 50 0 0 0 0 0 0 0 7 0 0 69 0 0 0 % Q
% Arg: 7 0 13 0 0 0 7 0 7 0 0 7 0 0 0 % R
% Ser: 0 0 0 75 0 0 0 75 13 7 0 0 7 7 0 % S
% Thr: 0 0 38 0 7 0 0 0 13 0 0 0 82 0 0 % T
% Val: 0 13 19 0 13 7 0 0 7 0 0 0 0 7 0 % V
% Trp: 13 0 7 0 0 0 69 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 7 0 0 0 0 0 7 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _