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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: GNB2L1 All Species: 51.21
Human Site: T105 Identified Species: 75.11
UniProt: P63244 Number Species: 15
    Phosphosite Substitution
    Charge Score: -0.07
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P63244 NP_006089.1 317 35077 T105 T R R F V G H T K D V L S V A
Chimpanzee Pan troglodytes Q5IS43 410 46712 T150 E R T L K G H T D S V Q D I S
Rhesus Macaque Macaca mulatta XP_001105066 393 42789 T181 T R R F V G H T K D V L S V A
Dog Lupus familis XP_537934 316 34871 T105 T R R F V G H T K D V L S V A
Cat Felis silvestris
Mouse Mus musculus Q8BHD1 476 53485 T144 L Y S L Y R H T H W V R C A K
Rat Rattus norvegicus P63245 317 35058 T105 T R R F V G H T K D V L S V A
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001511303 428 47737 T216 T R R F V G H T K D V L S V A
Chicken Gallus gallus Q9PTR5 410 46646 T150 E R T L K G H T D S V Q D I S
Frog Xenopus laevis Q6DE72 410 46731 T150 E R T L K G H T D S V Q D I S
Zebra Danio Brachydanio rerio O42248 317 35104 T105 T R R F V G H T K D V L S V A
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster O18640 318 35599 T106 T R R F E G H T K D V L S V A
Honey Bee Apis mellifera XP_392962 317 35737 T105 T R R F E D H T K D V L S V A
Nematode Worm Caenorhab. elegans Q21215 325 35812 T111 T R Q F I S H T K D V L S V A
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana O24456 327 35729 T105 T R R F V G H T K D V L S V A
Baker's Yeast Sacchar. cerevisiae P38011 319 34787 K107 Y Q R F V G H K S D V M S V D
Red Bread Mold Neurospora crassa Q01369 316 35112 T105 T R R F V G H T N D V L S V S
Conservation
Percent
Protein Identity: 100 23.4 80.6 99.3 N.A. 23.9 100 N.A. 74 23.6 23.8 95.5 N.A. 76.4 79.5 71.3 N.A.
Protein Similarity: 100 39.5 80.6 99.3 N.A. 37.1 100 N.A. 74 39.5 39.2 99.6 N.A. 86.4 88.3 82.4 N.A.
P-Site Identity: 100 33.3 100 100 N.A. 20 100 N.A. 100 33.3 33.3 100 N.A. 93.3 86.6 80 N.A.
P-Site Similarity: 100 46.6 100 100 N.A. 20 100 N.A. 100 46.6 46.6 100 N.A. 93.3 86.6 93.3 N.A.
Percent
Protein Identity: N.A. N.A. N.A. 65.4 52.9 70.6
Protein Similarity: N.A. N.A. N.A. 77.3 70.2 83.6
P-Site Identity: N.A. N.A. N.A. 100 60 86.6
P-Site Similarity: N.A. N.A. N.A. 100 73.3 93.3
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 0 0 0 0 0 0 0 7 63 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 7 0 0 % C
% Asp: 0 0 0 0 0 7 0 0 19 75 0 0 19 0 7 % D
% Glu: 19 0 0 0 13 0 0 0 0 0 0 0 0 0 0 % E
% Phe: 0 0 0 75 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 0 0 82 0 0 0 0 0 0 0 0 0 % G
% His: 0 0 0 0 0 0 100 0 7 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 7 0 0 0 0 0 0 0 0 19 0 % I
% Lys: 0 0 0 0 19 0 0 7 63 0 0 0 0 0 7 % K
% Leu: 7 0 0 25 0 0 0 0 0 0 0 69 0 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 7 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 7 0 0 0 0 0 0 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % P
% Gln: 0 7 7 0 0 0 0 0 0 0 0 19 0 0 0 % Q
% Arg: 0 88 69 0 0 7 0 0 0 0 0 7 0 0 0 % R
% Ser: 0 0 7 0 0 7 0 0 7 19 0 0 75 0 25 % S
% Thr: 69 0 19 0 0 0 0 94 0 0 0 0 0 0 0 % T
% Val: 0 0 0 0 57 0 0 0 0 0 100 0 0 75 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 7 0 0 0 0 0 % W
% Tyr: 7 7 0 0 7 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _