KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
GNB2L1
All Species:
50.3
Human Site:
Y246
Identified Species:
73.78
UniProt:
P63244
Number Species:
15
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P63244
NP_006089.1
317
35077
Y246
L
C
F
S
P
N
R
Y
W
L
C
A
A
T
G
Chimpanzee
Pan troglodytes
Q5IS43
410
46712
S289
I
S
W
A
P
E
S
S
Y
S
S
I
S
E
A
Rhesus Macaque
Macaca mulatta
XP_001105066
393
42789
Y322
L
C
F
S
P
N
R
Y
W
L
C
A
A
T
G
Dog
Lupus familis
XP_537934
316
34871
Y245
L
C
F
S
P
N
R
Y
W
L
C
A
A
T
G
Cat
Felis silvestris
Mouse
Mus musculus
Q8BHD1
476
53485
H335
Y
P
R
S
P
H
S
H
E
D
R
K
E
T
I
Rat
Rattus norvegicus
P63245
317
35058
Y246
L
C
F
S
P
N
R
Y
W
L
C
A
A
T
G
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001511303
428
47737
Y357
L
C
F
S
P
N
R
Y
W
L
C
A
A
T
G
Chicken
Gallus gallus
Q9PTR5
410
46646
S289
I
S
W
A
P
E
S
S
Y
S
T
I
S
E
A
Frog
Xenopus laevis
Q6DE72
410
46731
F310
K
S
G
K
P
G
P
F
L
L
S
G
S
R
D
Zebra Danio
Brachydanio rerio
O42248
317
35104
Y246
L
C
F
S
P
N
R
Y
W
L
C
A
A
T
G
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
O18640
318
35599
Y247
L
C
F
S
P
N
R
Y
W
L
C
V
A
Y
G
Honey Bee
Apis mellifera
XP_392962
317
35737
Y246
L
C
F
S
P
N
R
Y
W
L
C
A
A
F
G
Nematode Worm
Caenorhab. elegans
Q21215
325
35812
Y252
M
S
F
S
P
N
R
Y
W
L
C
A
A
V
G
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
O24456
327
35729
Y248
L
C
F
S
P
N
R
Y
W
L
C
A
A
T
E
Baker's Yeast
Sacchar. cerevisiae
P38011
319
34787
Y250
L
A
F
S
P
N
R
Y
W
L
A
A
A
T
A
Red Bread Mold
Neurospora crassa
Q01369
316
35112
Y246
L
V
F
S
P
N
R
Y
W
L
C
A
A
T
S
Conservation
Percent
Protein Identity:
100
23.4
80.6
99.3
N.A.
23.9
100
N.A.
74
23.6
23.8
95.5
N.A.
76.4
79.5
71.3
N.A.
Protein Similarity:
100
39.5
80.6
99.3
N.A.
37.1
100
N.A.
74
39.5
39.2
99.6
N.A.
86.4
88.3
82.4
N.A.
P-Site Identity:
100
6.6
100
100
N.A.
20
100
N.A.
100
6.6
13.3
100
N.A.
86.6
93.3
80
N.A.
P-Site Similarity:
100
40
100
100
N.A.
33.3
100
N.A.
100
40
26.6
100
N.A.
86.6
93.3
86.6
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
65.4
52.9
70.6
Protein Similarity:
N.A.
N.A.
N.A.
77.3
70.2
83.6
P-Site Identity:
N.A.
N.A.
N.A.
93.3
80
86.6
P-Site Similarity:
N.A.
N.A.
N.A.
93.3
80
86.6
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
7
0
13
0
0
0
0
0
0
7
69
75
0
19
% A
% Cys:
0
57
0
0
0
0
0
0
0
0
69
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
7
0
0
0
0
7
% D
% Glu:
0
0
0
0
0
13
0
0
7
0
0
0
7
13
7
% E
% Phe:
0
0
75
0
0
0
0
7
0
0
0
0
0
7
0
% F
% Gly:
0
0
7
0
0
7
0
0
0
0
0
7
0
0
57
% G
% His:
0
0
0
0
0
7
0
7
0
0
0
0
0
0
0
% H
% Ile:
13
0
0
0
0
0
0
0
0
0
0
13
0
0
7
% I
% Lys:
7
0
0
7
0
0
0
0
0
0
0
7
0
0
0
% K
% Leu:
69
0
0
0
0
0
0
0
7
82
0
0
0
0
0
% L
% Met:
7
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
75
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
7
0
0
100
0
7
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
7
0
0
0
75
0
0
0
7
0
0
7
0
% R
% Ser:
0
25
0
82
0
0
19
13
0
13
13
0
19
0
7
% S
% Thr:
0
0
0
0
0
0
0
0
0
0
7
0
0
63
0
% T
% Val:
0
7
0
0
0
0
0
0
0
0
0
7
0
7
0
% V
% Trp:
0
0
13
0
0
0
0
0
75
0
0
0
0
0
0
% W
% Tyr:
7
0
0
0
0
0
0
75
13
0
0
0
0
7
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _