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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
KCNJ2
All Species:
5.76
Human Site:
S413
Identified Species:
14.07
UniProt:
P63252
Number Species:
9
Phosphosite Substitution
Charge Score:
-0.22
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P63252
NP_000882.1
427
48288
S413
I
D
L
H
N
Q
A
S
V
P
L
E
P
R
P
Chimpanzee
Pan troglodytes
XP_001154349
535
59805
R516
Q
A
R
H
D
F
D
R
L
Q
A
G
G
G
V
Rhesus Macaque
Macaca mulatta
XP_001104273
433
48999
R414
Q
A
R
H
D
F
D
R
L
Q
A
G
S
G
A
Dog
Lupus familis
XP_546667
569
63060
A475
F
D
R
P
Q
A
S
A
A
A
L
Q
T
G
V
Cat
Felis silvestris
Mouse
Mus musculus
P35561
428
48371
A413
G
I
D
L
H
N
Q
A
S
V
P
L
E
P
R
Rat
Rattus norvegicus
Q64273
427
48182
S413
I
D
L
H
N
Q
A
S
V
P
L
E
P
R
P
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001507171
427
48351
G413
I
D
H
H
N
Q
A
G
V
P
L
E
P
R
P
Chicken
Gallus gallus
P52186
427
48500
G413
M
D
H
H
N
Q
A
G
V
P
L
E
P
R
P
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_001923086
427
48469
Q411
S
S
D
S
E
H
S
Q
A
T
V
P
L
E
P
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
P52192
505
57401
S445
L
N
H
F
Q
S
S
S
N
S
P
V
F
S
N
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
56.2
71.1
53.2
N.A.
98.3
98.8
N.A.
95.7
94.3
N.A.
84
N.A.
N.A.
N.A.
35.6
N.A.
Protein Similarity:
100
67.8
84.7
65.5
N.A.
98.8
99.3
N.A.
98.5
97.4
N.A.
92.7
N.A.
N.A.
N.A.
55.4
N.A.
P-Site Identity:
100
6.6
6.6
13.3
N.A.
0
100
N.A.
86.6
80
N.A.
6.6
N.A.
N.A.
N.A.
6.6
N.A.
P-Site Similarity:
100
20
20
33.3
N.A.
13.3
100
N.A.
86.6
86.6
N.A.
20
N.A.
N.A.
N.A.
26.6
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
20
0
0
0
10
40
20
20
10
20
0
0
0
10
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
50
20
0
20
0
20
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
0
0
10
0
0
0
0
0
0
40
10
10
0
% E
% Phe:
10
0
0
10
0
20
0
0
0
0
0
0
10
0
0
% F
% Gly:
10
0
0
0
0
0
0
20
0
0
0
20
10
30
0
% G
% His:
0
0
30
60
10
10
0
0
0
0
0
0
0
0
0
% H
% Ile:
30
10
0
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
10
0
20
10
0
0
0
0
20
0
50
10
10
0
0
% L
% Met:
10
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
10
0
0
40
10
0
0
10
0
0
0
0
0
10
% N
% Pro:
0
0
0
10
0
0
0
0
0
40
20
10
40
10
50
% P
% Gln:
20
0
0
0
20
40
10
10
0
20
0
10
0
0
0
% Q
% Arg:
0
0
30
0
0
0
0
20
0
0
0
0
0
40
10
% R
% Ser:
10
10
0
10
0
10
30
30
10
10
0
0
10
10
0
% S
% Thr:
0
0
0
0
0
0
0
0
0
10
0
0
10
0
0
% T
% Val:
0
0
0
0
0
0
0
0
40
10
10
10
0
0
20
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _