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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ACTG1
All Species:
40.61
Human Site:
T278
Identified Species:
99.26
UniProt:
P63261
Number Species:
9
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P63261
NP_001605.1
375
41793
T278
S
C
G
I
H
E
T
T
F
N
S
I
M
K
C
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_533132
375
41719
T278
S
C
G
I
H
E
T
T
F
N
S
I
M
K
C
Cat
Felis silvestris
Mouse
Mus musculus
Rat
Rattus norvegicus
P63259
375
41774
T278
S
C
G
I
H
E
T
T
F
N
S
I
M
K
C
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
P53478
376
41817
T279
S
C
G
I
H
E
T
T
F
N
S
I
M
K
C
Frog
Xenopus laevis
P53505
376
41831
T279
S
C
G
I
H
E
T
T
F
N
S
I
M
K
C
Zebra Danio
Brachydanio rerio
Q7ZVI7
375
41748
T278
S
C
G
I
H
E
T
T
F
N
S
I
M
K
C
Tiger Blowfish
Takifugu rubipres
P68142
375
41748
T278
S
C
G
I
H
E
T
T
Y
N
S
I
M
K
C
Fruit Fly
Dros. melanogaster
P10987
376
41803
T279
A
C
G
I
H
E
T
T
Y
N
S
I
M
K
C
Honey Bee
Apis mellifera
XP_393368
376
41787
T279
A
C
G
I
H
E
T
T
Y
N
S
I
M
K
C
Nematode Worm
Caenorhab. elegans
P10986
376
41759
S279
S
A
G
I
H
E
T
S
Y
N
S
I
M
K
C
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
N.A.
99.1
N.A.
N.A.
100
N.A.
N.A.
98.9
99.4
98.9
98.9
97.8
97.8
96.8
N.A.
Protein Similarity:
100
N.A.
N.A.
99.4
N.A.
N.A.
100
N.A.
N.A.
99.7
99.7
99.7
99.7
99.7
99.7
99.4
N.A.
P-Site Identity:
100
N.A.
N.A.
100
N.A.
N.A.
100
N.A.
N.A.
100
100
100
93.3
86.6
86.6
80
N.A.
P-Site Similarity:
100
N.A.
N.A.
100
N.A.
N.A.
100
N.A.
N.A.
100
100
100
100
100
100
93.3
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
20
10
0
0
0
0
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
90
0
0
0
0
0
0
0
0
0
0
0
0
100
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
0
0
0
100
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
60
0
0
0
0
0
0
% F
% Gly:
0
0
100
0
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
100
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
100
0
0
0
0
0
0
0
100
0
0
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
0
0
0
100
0
% K
% Leu:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
100
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
100
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
80
0
0
0
0
0
0
10
0
0
100
0
0
0
0
% S
% Thr:
0
0
0
0
0
0
100
90
0
0
0
0
0
0
0
% T
% Val:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
40
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _