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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ACTG2
All Species:
36.36
Human Site:
Y189
Identified Species:
100
UniProt:
P63267
Number Species:
8
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P63267
NP_001606.1
376
41877
Y189
A
G
R
D
L
T
D
Y
L
M
K
I
L
T
E
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
Cat
Felis silvestris
Mouse
Mus musculus
Rat
Rattus norvegicus
P63269
376
41858
Y189
A
G
R
D
L
T
D
Y
L
M
K
I
L
T
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506759
377
42004
Y190
A
G
R
D
L
T
D
Y
L
M
K
I
L
T
E
Chicken
Gallus gallus
P08023
377
41976
Y190
A
G
R
D
L
T
D
Y
L
M
K
I
L
S
E
Frog
Xenopus laevis
P04751
377
41997
Y190
A
G
R
D
L
T
D
Y
L
M
K
I
L
T
E
Zebra Danio
Brachydanio rerio
NP_997785
377
42037
Y190
A
G
R
D
L
T
D
Y
L
M
K
I
L
T
E
Tiger Blowfish
Takifugu rubipres
P53482
377
41958
Y190
A
G
R
D
L
T
D
Y
L
M
K
I
L
T
E
Fruit Fly
Dros. melanogaster
P10987
376
41803
Y189
A
G
R
D
L
T
D
Y
L
M
K
I
L
T
E
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
P10984
376
41759
Y189
A
G
R
D
L
T
D
Y
L
M
K
I
L
T
E
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
N.A.
N.A.
N.A.
N.A.
100
N.A.
98.9
98.9
98.4
98.6
98.4
94.1
N.A.
94.1
N.A.
Protein Similarity:
100
N.A.
N.A.
N.A.
N.A.
N.A.
100
N.A.
99.4
99.4
98.9
99.1
98.9
96.8
N.A.
97
N.A.
P-Site Identity:
100
N.A.
N.A.
N.A.
N.A.
N.A.
100
N.A.
100
93.3
100
100
100
100
N.A.
100
N.A.
P-Site Similarity:
100
N.A.
N.A.
N.A.
N.A.
N.A.
100
N.A.
100
100
100
100
100
100
N.A.
100
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
100
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
100
0
0
100
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
100
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
100
0
0
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
100
0
0
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
100
0
0
0
0
% K
% Leu:
0
0
0
0
100
0
0
0
100
0
0
0
100
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
100
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
100
0
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
0
0
0
0
0
0
0
0
0
0
0
0
0
12
0
% S
% Thr:
0
0
0
0
0
100
0
0
0
0
0
0
0
89
0
% T
% Val:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
100
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _