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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: TNNC1 All Species: 41.21
Human Site: Y111 Identified Species: 60.44
UniProt: P63316 Number Species: 15
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P63316 NP_003271.1 161 18403 Y111 F D K N A D G Y I D L D E L K
Chimpanzee Pan troglodytes XP_512771 270 29312 Y221 F D K D G N G Y I S A A E L R
Rhesus Macaque Macaca mulatta XP_001085656 165 18786 Y111 F D K N A D G Y I D L D E L K
Dog Lupus familis XP_533799 161 18370 Y111 F D K N A D G Y I D L D E L K
Cat Felis silvestris
Mouse Mus musculus P19123 161 18402 Y111 F D K N A D G Y I D L D E L K
Rat Rattus norvegicus P62161 149 16819 Y100 F D K D G N G Y I S A A E L R
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001505895 171 19435 Y121 F D K N A D G Y I D L E E L K
Chicken Gallus gallus P09860 161 18412 Y111 F D K N A D G Y I D L E E L K
Frog Xenopus laevis NP_001079398 163 18351 Y113 F D K N A D G Y I D G E E L A
Zebra Danio Brachydanio rerio NP_852475 161 18433 Y111 F D K N A D G Y I D L D E L K
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans O16305 149 16806 F100 F D K D G N G F I S A A E L R
Sea Urchin Strong. purpuratus XP_780862 149 16822 Y100 F D K D G N G Y I S A A E L R
Poplar Tree Populus trichocarpa XP_002330977 149 16843 F100 F D K D Q N G F I S A A E L R
Maize Zea mays NP_001105547 149 16813 F100 F D K D Q N G F I S A A E L R
Rice Oryza sativa
Thale Cress Arabidopsis thaliana P25854 149 16843 F100 F D K D Q N G F I S A A E L R
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa P61859 149 16978 F100 F D R D N N G F I S A A E L R
Conservation
Percent
Protein Identity: 100 29.6 91.5 99.3 N.A. 99.3 49 N.A. 88.8 98.7 63.1 89.4 N.A. N.A. N.A. 48.4 48.4
Protein Similarity: 100 44 94.5 100 N.A. 100 70.1 N.A. 91.8 100 80.3 96.2 N.A. N.A. N.A. 69.5 69.5
P-Site Identity: 100 53.3 100 100 N.A. 100 53.3 N.A. 93.3 93.3 80 100 N.A. N.A. N.A. 46.6 53.3
P-Site Similarity: 100 73.3 100 100 N.A. 100 73.3 N.A. 100 100 86.6 100 N.A. N.A. N.A. 73.3 73.3
Percent
Protein Identity: 49 49.6 N.A. 49 N.A. 47.8
Protein Similarity: 71.4 70.8 N.A. 71.4 N.A. 70.8
P-Site Identity: 46.6 46.6 N.A. 46.6 N.A. 40
P-Site Similarity: 73.3 73.3 N.A. 73.3 N.A. 73.3
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 50 0 0 0 0 0 50 50 0 0 7 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 100 0 50 0 50 0 0 0 50 0 32 0 0 0 % D
% Glu: 0 0 0 0 0 0 0 0 0 0 0 19 100 0 0 % E
% Phe: 100 0 0 0 0 0 0 32 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 0 25 0 100 0 0 0 7 0 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 100 0 0 0 0 0 0 % I
% Lys: 0 0 94 0 0 0 0 0 0 0 0 0 0 0 44 % K
% Leu: 0 0 0 0 0 0 0 0 0 0 44 0 0 100 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 50 7 50 0 0 0 0 0 0 0 0 0 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % P
% Gln: 0 0 0 0 19 0 0 0 0 0 0 0 0 0 0 % Q
% Arg: 0 0 7 0 0 0 0 0 0 0 0 0 0 0 50 % R
% Ser: 0 0 0 0 0 0 0 0 0 50 0 0 0 0 0 % S
% Thr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % T
% Val: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 69 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _