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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PPP2CA
All Species:
51.52
Human Site:
T301
Identified Species:
75.56
UniProt:
P67775
Number Species:
15
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P67775
NP_002706.1
309
35594
T301
R
R
G
E
P
H
V
T
R
R
T
P
D
Y
F
Chimpanzee
Pan troglodytes
XP_527011
309
35630
T301
R
R
G
E
P
H
V
T
R
R
T
P
D
Y
F
Rhesus Macaque
Macaca mulatta
XP_001084083
286
32771
D279
Q
A
A
I
M
E
L
D
D
T
L
K
Y
S
L
Dog
Lupus familis
XP_858531
311
35711
T303
R
R
G
E
P
H
V
T
R
R
T
P
D
Y
F
Cat
Felis silvestris
Mouse
Mus musculus
Rat
Rattus norvegicus
P63331
309
35590
T301
R
R
G
E
P
H
V
T
R
R
T
P
D
Y
F
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001512852
302
34248
T294
R
R
G
E
P
H
V
T
R
R
T
P
D
Y
F
Chicken
Gallus gallus
P48463
309
35545
T301
R
R
G
E
P
H
V
T
R
R
T
P
D
Y
F
Frog
Xenopus laevis
Q6IP91
307
35104
S298
Q
E
T
R
G
I
P
S
K
K
P
V
A
D
Y
Zebra Danio
Brachydanio rerio
A8WGP3
311
35438
S302
Q
E
T
R
G
L
P
S
K
K
P
V
A
D
Y
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P23696
309
35450
T301
R
R
G
E
P
H
V
T
R
R
T
P
D
Y
F
Honey Bee
Apis mellifera
XP_623105
309
35425
T301
R
R
G
E
P
H
V
T
R
R
T
P
D
Y
F
Nematode Worm
Caenorhab. elegans
Q9XW79
333
37341
K325
E
N
R
G
A
P
A
K
K
P
H
A
D
Y
F
Sea Urchin
Strong. purpuratus
XP_780423
308
35412
T300
R
R
G
E
P
H
V
T
R
R
T
P
D
Y
F
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q07100
313
35814
T305
R
R
G
E
P
D
V
T
R
R
T
P
D
Y
F
Baker's Yeast
Sacchar. cerevisiae
P23595
377
43028
T369
R
P
G
E
P
T
V
T
R
K
T
P
D
Y
F
Red Bread Mold
Neurospora crassa
P48580
327
37273
S319
R
A
G
E
P
M
V
S
R
R
T
P
D
Y
F
Conservation
Percent
Protein Identity:
100
99
89.9
96.7
N.A.
N.A.
99.6
N.A.
90.9
98
66
64.6
N.A.
93.8
96.1
59.1
93.5
Protein Similarity:
100
99
91.9
98.7
N.A.
N.A.
100
N.A.
93.1
99
81.5
81
N.A.
98.7
98
74.7
96.7
P-Site Identity:
100
100
0
100
N.A.
N.A.
100
N.A.
100
100
0
0
N.A.
100
100
20
100
P-Site Similarity:
100
100
13.3
100
N.A.
N.A.
100
N.A.
100
100
33.3
33.3
N.A.
100
100
26.6
100
Percent
Protein Identity:
N.A.
N.A.
N.A.
78.5
62.6
81.3
Protein Similarity:
N.A.
N.A.
N.A.
87.2
71.8
86.8
P-Site Identity:
N.A.
N.A.
N.A.
93.3
80
80
P-Site Similarity:
N.A.
N.A.
N.A.
93.3
86.6
86.6
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
13
7
0
7
0
7
0
0
0
0
7
13
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
7
0
7
7
0
0
0
82
13
0
% D
% Glu:
7
13
0
75
0
7
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
82
% F
% Gly:
0
0
75
7
13
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
57
0
0
0
0
7
0
0
0
0
% H
% Ile:
0
0
0
7
0
7
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
0
0
7
19
19
0
7
0
0
0
% K
% Leu:
0
0
0
0
0
7
7
0
0
0
7
0
0
0
7
% L
% Met:
0
0
0
0
7
7
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
7
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
7
0
0
75
7
13
0
0
7
13
75
0
0
0
% P
% Gln:
19
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
75
63
7
13
0
0
0
0
75
69
0
0
0
0
0
% R
% Ser:
0
0
0
0
0
0
0
19
0
0
0
0
0
7
0
% S
% Thr:
0
0
13
0
0
7
0
69
0
7
75
0
0
0
0
% T
% Val:
0
0
0
0
0
0
75
0
0
0
0
13
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
7
82
13
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _