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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: YBX1 All Species: 30.3
Human Site: Y281 Identified Species: 60.61
UniProt: P67809 Number Species: 11
    Phosphosite Substitution
    Charge Score: 0.09
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P67809 NP_004550.2 324 35924 Y281 Q Q P P Q R R Y R R N F N Y R
Chimpanzee Pan troglodytes XP_525693 483 52625 Y440 Q Q P P Q R R Y R R N F N Y R
Rhesus Macaque Macaca mulatta XP_001088540 450 49055 Y407 Q Q P P Q R R Y R R N F N Y R
Dog Lupus familis XP_848371 326 36048 Y283 Q Q P P Q R R Y R R N F N Y R
Cat Felis silvestris
Mouse Mus musculus Q9JKB3 361 38795 F318 Q P S A R R G F R R P Y N Y R
Rat Rattus norvegicus P62961 322 35711 Y279 Q Q P P Q R R Y R R N F N Y R
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001515006 316 36033 Y273 Q Q P P Q R R Y R R N F N Y R
Chicken Gallus gallus Q06066 321 35781 Y278 Q Q P P Q R R Y R R N F N Y R
Frog Xenopus laevis Q00436 305 34466 Y262 A C H L M R R Y R R N F N Y R
Zebra Danio Brachydanio rerio Q803L0 202 21867 V163 C Q S I S H M V A N C P I K A
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9VRN5 195 21575 E156 R C H R C R G E D H L H A D C
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q38896 201 19059 G162 G G G Y S G G G G G G R Y G S
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 67 72 99 N.A. 57.3 98.7 N.A. 84.2 90.7 79.9 20.3 N.A. 22.2 N.A. N.A. N.A.
Protein Similarity: 100 67 72 99.3 N.A. 63.7 99 N.A. 86.7 94.7 84.5 31.1 N.A. 34.5 N.A. N.A. N.A.
P-Site Identity: 100 100 100 100 N.A. 46.6 100 N.A. 100 100 66.6 6.6 N.A. 6.6 N.A. N.A. N.A.
P-Site Similarity: 100 100 100 100 N.A. 66.6 100 N.A. 100 100 66.6 6.6 N.A. 13.3 N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. 22.8 N.A. N.A.
Protein Similarity: N.A. N.A. N.A. 31.7 N.A. N.A.
P-Site Identity: N.A. N.A. N.A. 0 N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. 0 N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 9 0 0 9 0 0 0 0 9 0 0 0 9 0 9 % A
% Cys: 9 17 0 0 9 0 0 0 0 0 9 0 0 0 9 % C
% Asp: 0 0 0 0 0 0 0 0 9 0 0 0 0 9 0 % D
% Glu: 0 0 0 0 0 0 0 9 0 0 0 0 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 9 0 0 0 67 0 0 0 % F
% Gly: 9 9 9 0 0 9 25 9 9 9 9 0 0 9 0 % G
% His: 0 0 17 0 0 9 0 0 0 9 0 9 0 0 0 % H
% Ile: 0 0 0 9 0 0 0 0 0 0 0 0 9 0 0 % I
% Lys: 0 0 0 0 0 0 0 0 0 0 0 0 0 9 0 % K
% Leu: 0 0 0 9 0 0 0 0 0 0 9 0 0 0 0 % L
% Met: 0 0 0 0 9 0 9 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 9 67 0 75 0 0 % N
% Pro: 0 9 59 59 0 0 0 0 0 0 9 9 0 0 0 % P
% Gln: 67 67 0 0 59 0 0 0 0 0 0 0 0 0 0 % Q
% Arg: 9 0 0 9 9 84 67 0 75 75 0 9 0 0 75 % R
% Ser: 0 0 17 0 17 0 0 0 0 0 0 0 0 0 9 % S
% Thr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % T
% Val: 0 0 0 0 0 0 0 9 0 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 9 0 0 0 67 0 0 0 9 9 75 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _