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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: CSNK2B All Species: 23.31
Human Site: S209 Identified Species: 42.74
UniProt: P67870 Number Species: 12
    Phosphosite Substitution
    Charge Score: -0.08
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P67870 NP_001311.3 215 24942 S209 Q A A S N F K S P V K T I R _
Chimpanzee Pan troglodytes
Rhesus Macaque Macaca mulatta XP_001112540 234 26907 S228 Q A A S N F K S P V K T I R _
Dog Lupus familis XP_532075 304 34323 S298 Q A A S N F K S P V K T I R _
Cat Felis silvestris
Mouse Mus musculus NP_034105 215 24924 S209 Q A A S N F K S P V K T I R _
Rat Rattus norvegicus
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus
Frog Xenopus laevis P28021 215 24942 S209 Q A A S N F K S P V K T M R _
Zebra Danio Brachydanio rerio Q91398 215 24867 S209 Q A A S S F K S P V K A I R _
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P08182 235 27069 M209 Q A A A N F K M P L R A Q R G
Honey Bee Apis mellifera XP_624048 221 25542 A209 Q S A S T F K A P L R A V N Y
Nematode Worm Caenorhab. elegans P28548 234 26417 A208 G N S G G N T A N N V A A A Q
Sea Urchin Strong. purpuratus XP_780696 223 25844 R209 Q A A A A R S R S S T S R Q R
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana P40228 287 32336 Y275 P A K A T Q N Y V Q R V F G F
Baker's Yeast Sacchar. cerevisiae P38930 258 29824 L239 Q E L Q R L K L V E K L E S K
Red Bread Mold Neurospora crassa Q8TG11 285 32554 M213 Q N S Q R D E M R R R L R K L
Conservation
Percent
Protein Identity: 100 N.A. 91.8 70.7 N.A. 100 N.A. N.A. N.A. N.A. 99.5 99 N.A. 81.6 86.4 71.3 84.7
Protein Similarity: 100 N.A. 91.8 70.7 N.A. 100 N.A. N.A. N.A. N.A. 100 99.5 N.A. 88 93.2 81.6 91
P-Site Identity: 100 N.A. 100 100 N.A. 100 N.A. N.A. N.A. N.A. 92.8 85.7 N.A. 53.3 40 0 20
P-Site Similarity: 100 N.A. 100 100 N.A. 100 N.A. N.A. N.A. N.A. 100 92.8 N.A. 80 80 13.3 40
Percent
Protein Identity: N.A. N.A. N.A. 41.4 40.3 39.3
Protein Similarity: N.A. N.A. N.A. 50.8 55.8 54.3
P-Site Identity: N.A. N.A. N.A. 6.6 20 6.6
P-Site Similarity: N.A. N.A. N.A. 20 20 33.3
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 70 70 24 8 0 0 16 0 0 0 31 8 8 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 8 0 0 0 0 0 0 0 0 0 % D
% Glu: 0 8 0 0 0 0 8 0 0 8 0 0 8 0 0 % E
% Phe: 0 0 0 0 0 62 0 0 0 0 0 0 8 0 8 % F
% Gly: 8 0 0 8 8 0 0 0 0 0 0 0 0 8 8 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 0 0 0 0 39 0 0 % I
% Lys: 0 0 8 0 0 0 70 0 0 0 54 0 0 8 8 % K
% Leu: 0 0 8 0 0 8 0 8 0 16 0 16 0 0 8 % L
% Met: 0 0 0 0 0 0 0 16 0 0 0 0 8 0 0 % M
% Asn: 0 16 0 0 47 8 8 0 8 8 0 0 0 8 0 % N
% Pro: 8 0 0 0 0 0 0 0 62 0 0 0 0 0 0 % P
% Gln: 85 0 0 16 0 8 0 0 0 8 0 0 8 8 8 % Q
% Arg: 0 0 0 0 16 8 0 8 8 8 31 0 16 54 8 % R
% Ser: 0 8 16 54 8 0 8 47 8 8 0 8 0 8 0 % S
% Thr: 0 0 0 0 16 0 8 0 0 0 8 39 0 0 0 % T
% Val: 0 0 0 0 0 0 0 0 16 47 8 8 8 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 8 0 0 0 0 0 0 8 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 47 % _